21463628

Source:http://linkedlifedata.com/resource/pubmed/id/21463628

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0021107, umls-concept:C0086418, umls-concept:C0224394
pubmed:issue	1
pubmed:dateCreated	2011-7-4
pubmed:abstractText	To restore fecal continence, the weakened pressure of the internal anal sphincter (IAS) must be increased. We bioengineered intrinsically innervated human IAS to emulate sphincteric physiology in vitro.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/1RC1DK087151, http://linkedlifedata.com/resource/pubmed/grant/R01 DK071614-05, http://linkedlifedata.com/resource/pubmed/grant/R01 DK080684-03, http://linkedlifedata.com/resource/pubmed/grant/R01DK071614, http://linkedlifedata.com/resource/pubmed/grant/R01DK080684, http://linkedlifedata.com/resource/pubmed/grant/RC1 DK087151-02, http://linkedlifedata.com/resource/pubmed/grant/T32 HD007505-13, http://linkedlifedata.com/resource/pubmed/grant/T32HD007505
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/0374630
pubmed:citationSubset	AIM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Cholinergic Agonists, http://linkedlifedata.com/resource/pubmed/chemical/Enzyme Inhibitors, http://linkedlifedata.com/resource/pubmed/chemical/Homeodomain Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Hormone Antagonists, http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide Synthase, http://linkedlifedata.com/resource/pubmed/chemical/RAG-1 protein, http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Vasoactive Intestinal..., http://linkedlifedata.com/resource/pubmed/chemical/Vasoactive Intestinal Peptide
pubmed:status	MEDLINE
pubmed:month	Jul
pubmed:issn	1528-0012
pubmed:author	pubmed-author:BitarKhalil NKN, pubmed-author:GilmontRobert RRR, pubmed-author:MiyasakaEiichi AEA, pubmed-author:RaghavanShreyaS, pubmed-author:SomaraSitaS, pubmed-author:SrinivasanShanthiS, pubmed-author:TeitelbaumDaniel HDH
pubmed:copyrightInfo	Copyright © 2011 AGA Institute. Published by Elsevier Inc. All rights reserved.
pubmed:issnType	Electronic
pubmed:volume	141
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	310-9
pubmed:dateRevised	2011-9-26
pubmed:meshHeading	pubmed-meshheading:21463628-Anal Canal, pubmed-meshheading:21463628-Animals, pubmed-meshheading:21463628-Bioartificial Organs, pubmed-meshheading:21463628-Cells, Cultured, pubmed-meshheading:21463628-Cholinergic Agonists, pubmed-meshheading:21463628-Coculture Techniques, pubmed-meshheading:21463628-Electric Stimulation, pubmed-meshheading:21463628-Enzyme Inhibitors, pubmed-meshheading:21463628-Gastrointestinal Motility, pubmed-meshheading:21463628-Graft Survival, pubmed-meshheading:21463628-Homeodomain Proteins, pubmed-meshheading:21463628-Hormone Antagonists, pubmed-meshheading:21463628-Humans, pubmed-meshheading:21463628-Mice, pubmed-meshheading:21463628-Mice, Knockout, pubmed-meshheading:21463628-Muscle, Smooth, pubmed-meshheading:21463628-Muscle Contraction, pubmed-meshheading:21463628-Muscle Relaxation, pubmed-meshheading:21463628-Neovascularization, Physiologic, pubmed-meshheading:21463628-Nitric Oxide Synthase, pubmed-meshheading:21463628-Receptors, Vasoactive Intestinal Peptide, pubmed-meshheading:21463628-Time Factors, pubmed-meshheading:21463628-Tissue Engineering, pubmed-meshheading:21463628-Transplantation, Heterologous, pubmed-meshheading:21463628-Vasoactive Intestinal Peptide
pubmed:year	2011
pubmed:articleTitle	Successful implantation of bioengineered, intrinsically innervated, human internal anal sphincter.
pubmed:affiliation	GI Molecular Motors Lab, Department of Pediatrics-Gastroenterology, University of Michigan Medical School, Ann Arbor, Michigan 48109-0658, USA.
pubmed:publicationType	Journal Article, Research Support, N.I.H., Extramural