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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
2011-6-9
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pubmed:abstractText |
MicroRNAs (miRNAs) are a novel group of small non-coding RNAs that regulate gene expression at the post-transcriptional level and act on their target mRNAs in a tissue- and cell-type-specific manner. Herein, the relevance of MIR221/MIR222 in high-glucose- and AGE-mediated vascular damage was investigated.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1432-0428
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
54
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1930-40
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pubmed:meshHeading |
pubmed-meshheading:21461636-Animals,
pubmed-meshheading:21461636-Cell Line,
pubmed-meshheading:21461636-Cells, Cultured,
pubmed-meshheading:21461636-Cyclin-Dependent Kinase Inhibitor p27,
pubmed-meshheading:21461636-Cyclin-Dependent Kinase Inhibitor p57,
pubmed-meshheading:21461636-Endothelial Cells,
pubmed-meshheading:21461636-Flow Cytometry,
pubmed-meshheading:21461636-Gene Expression Regulation,
pubmed-meshheading:21461636-Glucose,
pubmed-meshheading:21461636-Glycosylation End Products, Advanced,
pubmed-meshheading:21461636-Humans,
pubmed-meshheading:21461636-Leukocytes, Mononuclear,
pubmed-meshheading:21461636-Mice,
pubmed-meshheading:21461636-MicroRNAs,
pubmed-meshheading:21461636-Polymerase Chain Reaction
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pubmed:year |
2011
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pubmed:articleTitle |
MIR221/MIR222-driven post-transcriptional regulation of P27KIP1 and P57KIP2 is crucial for high-glucose- and AGE-mediated vascular cell damage.
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pubmed:affiliation |
Department of Internal Medicine, University of Torino, Corso Dogliotti 14, 10126 Torino, Italy.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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