21459689

Source:http://linkedlifedata.com/resource/pubmed/id/21459689

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0242604
pubmed:issue	4
pubmed:dateCreated	2011-4-18
pubmed:abstractText	Thyroid hormone resistance syndromes are a group of genetic conditions characterized by decreased tissue sensitivity to thyroid hormones. Three syndromes, in which resistance to hormone action is respectively due to mutations in the gene encoding for thyroid hormone receptor TR?, impaired T4 and T3 transport, and impaired conversion of T4 to T3 mediated by deiodinases. An updated review of each of these forms of resistance is provided, and their pathogenetic mechanisms and clinical approaches are discussed.
pubmed:language	spa
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/100886482
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Iodide Peroxidase, http://linkedlifedata.com/resource/pubmed/chemical/Monocarboxylic Acid Transporters, http://linkedlifedata.com/resource/pubmed/chemical/SLC16A2 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Thyroid Hormone Receptors beta, http://linkedlifedata.com/resource/pubmed/chemical/Thyroid Hormones
pubmed:status	MEDLINE
pubmed:month	Apr
pubmed:issn	1579-2021
pubmed:author	pubmed-author:BernalJuanJ
pubmed:copyrightInfo	Copyright © 2010 SEEN. Published by Elsevier Espana. All rights reserved.
pubmed:issnType	Electronic
pubmed:volume	58
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	185-96
pubmed:meshHeading	pubmed-meshheading:21459689-Animals, pubmed-meshheading:21459689-Biological Transport, pubmed-meshheading:21459689-Cell Nucleus, pubmed-meshheading:21459689-Disease Models, Animal, pubmed-meshheading:21459689-Gene Expression Regulation, pubmed-meshheading:21459689-Genes, Recessive, pubmed-meshheading:21459689-Hormone Replacement Therapy, pubmed-meshheading:21459689-Humans, pubmed-meshheading:21459689-Hypothyroidism, pubmed-meshheading:21459689-Iodide Peroxidase, pubmed-meshheading:21459689-Mice, pubmed-meshheading:21459689-Mice, Knockout, pubmed-meshheading:21459689-Monocarboxylic Acid Transporters, pubmed-meshheading:21459689-Protein Structure, Tertiary, pubmed-meshheading:21459689-Response Elements, pubmed-meshheading:21459689-Syndrome, pubmed-meshheading:21459689-Thyroid Hormone Receptors beta, pubmed-meshheading:21459689-Thyroid Hormones
pubmed:year	2011
pubmed:articleTitle	[Thyroid hormone resistance syndromes].
pubmed:affiliation	Instituto de Investigaciones Biomédicas, CSIC-UAM y CIBER de enfermedades raras, Madrid, España. jbernal@iib.uam.es
pubmed:publicationType	Journal Article, English Abstract, Review, Research Support, Non-U.S. Gov't