Linked Life Data

21459126

Source:http://linkedlifedata.com/resource/pubmed/id/21459126

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2011-6-13
pubmed:abstractText
In humans, growth hormone (GH) is secreted from the anterior pituitary in a pulsatile pattern. The traditional view is that this secretory pattern is driven by two counter regulatory neurohormones, GHRH and somatostatin. Ghrelin, the natural ligand for the growth hormone (GH)-secretagogue receptor (GHS-R), is produced in the stomach. Ghrelin is the strongest GH secretagogue known to date, but the role of endogenous ghrelin in the regulation of circulating GH levels remains controversial. The following review examines the evidence suggesting that endogenous ghrelin may be a key regulator of GH peak amplitude and discusses studies of diseases with altered GH levels, where it is found that in these states GH and ghrelin levels change in a similar way.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
1872-8057
pubmed:author
pubmed:copyrightInfo
Copyright © 2011. Published by Elsevier Ireland Ltd.
pubmed:issnType
Electronic
pubmed:day
20
pubmed:volume
340
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
10-4
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
The role of ghrelin in GH secretion and GH disorders.
pubmed:affiliation
University of Virginia, Charlottesville, VA, USA.
pubmed:publicationType
Journal Article, Review