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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
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pubmed:dateCreated |
1990-12-27
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pubmed:abstractText |
Seventy-four post-menopausal women with metastatic breast cancer were treated with a combination hormonal regimen consisting of tamoxifen, aminoglutethimide danazol and medroxyprogesterone acetate (POND). 72% of the patients had received no previous treatment. The overall response rate (complete and partial remission) was 43.5% with a median response duration of 19 months and a median survival of 27 months. The most common sites of response were in regional nodes and local chest wall disease. The major side-effects were those expected from the individual agents: nausea, lethargy, rash and oedema.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0959-8049
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
26
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
824-7
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pubmed:dateRevised |
2006-4-24
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pubmed:meshHeading |
pubmed-meshheading:2145904-Aged,
pubmed-meshheading:2145904-Aged, 80 and over,
pubmed-meshheading:2145904-Aminoglutethimide,
pubmed-meshheading:2145904-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:2145904-Breast Neoplasms,
pubmed-meshheading:2145904-Danazol,
pubmed-meshheading:2145904-Female,
pubmed-meshheading:2145904-Humans,
pubmed-meshheading:2145904-Medroxyprogesterone,
pubmed-meshheading:2145904-Middle Aged,
pubmed-meshheading:2145904-Neoplasm Metastasis,
pubmed-meshheading:2145904-Tamoxifen
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pubmed:year |
1990
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pubmed:articleTitle |
Combination of tamoxifen, aminoglutethimide, danazol and medroxyprogesterone acetate in advanced breast cancer.
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pubmed:affiliation |
Department of Medicine, Royal Marsden Hospital, Surrey, U.K.
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pubmed:publicationType |
Journal Article
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