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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
1990-11-19
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pubmed:abstractText |
A simple enzyme immunoassay measuring human chorionic gonadotropin in undiluted maternal serum has been developed in order to be used as a prenatal screening test for Down's syndrome. A retrospective study of maternal serum sampled during pregnancies associated with trisomy 21 shows that with a 5% amniocentesis rate determined on a single test, the detection rate of trisomy 21 would be around two-thirds of the affected pregnancies. A prospective study of 9040 pregnant women under 38 years has confirmed the usefulness of the assay.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0197-3851
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
389-98
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2145556-Adult,
pubmed-meshheading:2145556-African Continental Ancestry Group,
pubmed-meshheading:2145556-Blood Chemical Analysis,
pubmed-meshheading:2145556-Chorionic Gonadotropin,
pubmed-meshheading:2145556-Down Syndrome,
pubmed-meshheading:2145556-European Continental Ancestry Group,
pubmed-meshheading:2145556-Female,
pubmed-meshheading:2145556-Humans,
pubmed-meshheading:2145556-Immunoenzyme Techniques,
pubmed-meshheading:2145556-Maternal Age,
pubmed-meshheading:2145556-Pregnancy,
pubmed-meshheading:2145556-Pregnancy Trimester, Second,
pubmed-meshheading:2145556-Prenatal Diagnosis,
pubmed-meshheading:2145556-Prospective Studies,
pubmed-meshheading:2145556-Retrospective Studies
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pubmed:year |
1990
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pubmed:articleTitle |
A single chorionic gonadotropin assay for maternal serum screening for Down's syndrome.
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pubmed:affiliation |
INSERM U 73, Paris, France.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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