Linked Life Data

21455396

Source:http://linkedlifedata.com/resource/pubmed/id/21455396

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2011-4-1
pubmed:abstractText
Effect of the extent of motor seizure modification on cardiovascular responses in ECT was studied at the second ECT session in 50 (ULECT=25) consenting patients. Twenty five patients each received either 0.5 mg/kg or 1 mg/kg of succinylcholine in a random design. Blood pressure and heart rate were recorded on five occasions during the ECT session. Extent of motor seizure was assessed on a five point scale by two raters blind to succinylcholine dose. Two raters had good interrater agreement on the scale. Significantly more patients had poor modification with 0.5 mg/kg (68%) than with 1 mg/kg (12%) of succinylcholine. Rate-pressure-product (RPP=systolic BPx Heart rate) significantly changed over the five occasions, maximal being in ictal occasion, but the two succinylcholine dose groups did not differ. Ictal RPP positively correlated with post-anaesthesia RPP, ECT stimulus dose, seizure threshold and both seizure durations (Motor and EEG). Likewise, postictal RPP correlated with seizure threshold and actual ECT stimulus dose. Neither correlated with the motor seizure modification scores. In multiple, stepwise, linear regression models neither ictal nor post-ictal RPP variance was significantly explained by the extent of motor seizure modification scores. Hence, RPP changes during ECT may be reflecting cerebral mechanisms of ECT.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:status
PubMed-not-MEDLINE
pubmed:month
Jul
pubmed:issn
0019-5545
pubmed:author
pubmed:issnType
Print
pubmed:volume
41
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
236-41
pubmed:dateRevised
2011-7-28
pubmed:year
1999
pubmed:articleTitle
Cardiovascular response to ect is unaffected by extent of motor seizure modification.
pubmed:affiliation
N. MURALI, DPM., Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore-560 029.
pubmed:publicationType
Journal Article