Source:http://linkedlifedata.com/resource/pubmed/id/21454951
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
2011-5-17
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pubmed:abstractText |
The lung is one of the sites of granulomatous responses, which are characterized by the recruitment and organization of activated macrophages and lymphocytes. There have been several reports that have shown that some pulmonary granulomatous diseases, such as sarcoidosis and nontuberculous mycobacterial disease, are likely to be characterized by a preponderance in postmenopausal females. Although sex hormones have been shown to play an important role in the regulation of the immune system, the influence of sex hormones on pulmonary granuloma formation is still unclear. Objectives: The purpose of this study was to assess whether sex hormones are involved in granulomatous inflammation and to evaluate how sex hormones modulate this response in the lung.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
1423-0356
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pubmed:author |
pubmed-author:AnnouraTakeshiT,
pubmed-author:HashimotoMuneakiM,
pubmed-author:IshiwataToshijiT,
pubmed-author:IwakamiShinichiroS,
pubmed-author:MinakataKunihikoK,
pubmed-author:MiuraKayoK,
pubmed-author:MurakamiAkikoA,
pubmed-author:NaraTakeshiT,
pubmed-author:SasakiShinichiS,
pubmed-author:TajimaKenK,
pubmed-author:TakahashiFumiyukiF,
pubmed-author:TakahashiKazuhisaK,
pubmed-author:YoshiokaMasatakaM
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pubmed:copyrightInfo |
Copyright © 2011 S. Karger AG, Basel.
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pubmed:issnType |
Electronic
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pubmed:volume |
81
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
491-8
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pubmed:meshHeading |
pubmed-meshheading:21454951-Animals,
pubmed-meshheading:21454951-Bronchoalveolar Lavage Fluid,
pubmed-meshheading:21454951-Cytokines,
pubmed-meshheading:21454951-Female,
pubmed-meshheading:21454951-Freund's Adjuvant,
pubmed-meshheading:21454951-Gonadal Steroid Hormones,
pubmed-meshheading:21454951-Granuloma,
pubmed-meshheading:21454951-Lung Diseases,
pubmed-meshheading:21454951-Ovariectomy,
pubmed-meshheading:21454951-Rats,
pubmed-meshheading:21454951-Th1 Cells
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pubmed:year |
2011
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pubmed:articleTitle |
Sex hormones alter Th1 responses and enhance granuloma formation in the lung.
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pubmed:affiliation |
Department of Respiratory Medicine, School of Medicine, Juntendo University, Tokyo, Japan. tajiken @ juntendo.ac.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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