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rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
6
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pubmed:dateCreated |
2011-5-19
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pubmed:abstractText |
We studied the penetration of raltegravir and HIV shedding in the genital tract among 14 HIV-1-infected women receiving a raltegravir-containing regimen who had <40 copies/ml blood plasma (BP) HIV RNA. None of the cervicovaginal fluid (CVF) samples showed detectable HIV RNA. Median raltegravir concentrations were 235 ng/ml in BP and 93 ng/ml in CVF, with a CVF/BP ratio of approximately 2.3. This good penetration of raltegravir may contribute to the control of viral replication in the female genital tract.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
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pubmed:month |
Jun
|
|
pubmed:issn |
1098-6596
|
|
pubmed:author |
pubmed-author:BissuelFrançoisF,
pubmed-author:ClavelCyrilC,
pubmed-author:Crenn-HebertCatherineC,
pubmed-author:FerreiraClaudiaC,
pubmed-author:HeardIsabelleI,
pubmed-author:IchouHouriaH,
pubmed-author:KatlamaChristineC,
pubmed-author:MandelbrotLaurentL,
pubmed-author:MarcelinAnne-GenevièveAG,
pubmed-author:PeytavinGillesG,
pubmed-author:SouliéCathiaC,
pubmed-author:TubianaRolandR
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pubmed:issnType |
Electronic
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pubmed:volume |
55
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
3018-21
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pubmed:meshHeading |
|
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pubmed:year |
2011
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pubmed:articleTitle |
Raltegravir concentrations in the genital tract of HIV-1-infected women treated with a raltegravir-containing regimen (DIVA 01 study).
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pubmed:affiliation |
Department of Infectious Diseases, Pitié-Salpêtrière Hospital, Boulevard de l'Hôpital, Paris 75013, France. drcyrilclavel@yahoo.fr
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
