Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2011-4-18
pubmed:abstractText
There is increasing evidence that there is a strong relationship between brain oscillations and neurocognitive function. We used EEG power spectral analysis to determine if frequency and power provide an independent measure of developmental impairment in infants. We examined the spectral power of EEGs in 200 infants between 6 and 24 months of age who were evaluated for seizures. Infants were stratified into three age groups 6-12, 12-18, and 18-24 months, and development assessments were coded as normal, moderately delayed, and severely delayed. Compared with the normal infants, children with developmental delay had lower mean frequencies and greater delta and less theta and alpha power. Delta/theta and theta/alpha ratios were highly significant indicators of developmental status. This study demonstrates that frequency and power of brain oscillations during wakefulness is a strong predictor of development in infants. The findings support the concept that normal oscillatory activity is critical for normal cognitive function during development.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1525-5069
pubmed:author
pubmed:copyrightInfo
Copyright © 2011 Elsevier Inc. All rights reserved.
pubmed:issnType
Electronic
pubmed:volume
20
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
700-5
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
Power spectral analysis in infants with seizures: relationship to development.
pubmed:affiliation
Department of Neurology, Neuroscience Center at Dartmouth, Dartmouth Medical School, Hanover, NH 03756, USA.
pubmed:publicationType
Journal Article, Research Support, N.I.H., Extramural