rdf:type |
|
lifeskim:mentions |
umls-concept:C0006142,
umls-concept:C0016741,
umls-concept:C0019638,
umls-concept:C0027627,
umls-concept:C0200932,
umls-concept:C0205547,
umls-concept:C0456904,
umls-concept:C0683941,
umls-concept:C0746922,
umls-concept:C1306673,
umls-concept:C1510438,
umls-concept:C1521991,
umls-concept:C1522495,
umls-concept:C1706163,
umls-concept:C2697524,
umls-concept:C2700445
|
pubmed:issue |
19
|
pubmed:dateCreated |
2011-9-19
|
pubmed:abstractText |
Conventional histopathological examination is limited in measuring accurate total metastatic volume in a lymph node. Recently, a molecular-based procedure to detect lymph node metastases, one-step nucleic acid amplification (OSNA) assay, has been developed. OSNA assay can assess a whole lymph node and yields semiquantitative results. The authors compared the performance in intraoperative detection of sentinel lymph node metastases with OSNA assay using a whole lymph node versus routine frozen section (FS) histology with a 2 mm-sectioned lymph node.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
1097-0142
|
pubmed:author |
|
pubmed:copyrightInfo |
Copyright © 2011 American Cancer Society.
|
pubmed:issnType |
Electronic
|
pubmed:day |
1
|
pubmed:volume |
117
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
4365-74
|
pubmed:meshHeading |
pubmed-meshheading:21437889-Adult,
pubmed-meshheading:21437889-Aged,
pubmed-meshheading:21437889-Aged, 80 and over,
pubmed-meshheading:21437889-Breast Neoplasms,
pubmed-meshheading:21437889-Carcinoma, Ductal, Breast,
pubmed-meshheading:21437889-Carcinoma, Lobular,
pubmed-meshheading:21437889-Cohort Studies,
pubmed-meshheading:21437889-DNA, Neoplasm,
pubmed-meshheading:21437889-Female,
pubmed-meshheading:21437889-Frozen Sections,
pubmed-meshheading:21437889-Humans,
pubmed-meshheading:21437889-Lymph Nodes,
pubmed-meshheading:21437889-Lymphatic Metastasis,
pubmed-meshheading:21437889-Middle Aged,
pubmed-meshheading:21437889-Neoplasm Staging,
pubmed-meshheading:21437889-Nucleic Acid Amplification Techniques,
pubmed-meshheading:21437889-Prognosis,
pubmed-meshheading:21437889-Retrospective Studies,
pubmed-meshheading:21437889-Sentinel Lymph Node Biopsy
|
pubmed:year |
2011
|
pubmed:articleTitle |
Intraoperative molecular assay for sentinel lymph node metastases in early stage breast cancer: a comparative analysis between one-step nucleic acid amplification whole node assay and routine frozen section histology.
|
pubmed:affiliation |
Division of Pathology, the Cancer Institute of the Japanese Foundation for Cancer Research, Tokyo, Japan. tomo.osako@jfcr.or.jp
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|