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pubmed:abstractText |
Curcumin, the active ingredient from turmeric rhizomes, has been shown to have a wide range of pharmacological properties including antioxidant and anti-inflammatory effects. Curcumin has been reviewed for its multiple molecular action on inhibiting tumor angiogenesis via its mechanisms of cyclooxygenase (COX)-2, and vascular endothelial growth factor (VEGF) inhibition. In this present study, we aimed to assess the effects of curcumin on preventing diabetes-induced vascular dysfunction in association with COX-2, nuclear factor-?B (NF-?B) expression, and prostanoid production.
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pubmed:affiliation |
Interdepartment of Physiology, Graduate School, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
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