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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
17
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pubmed:dateCreated |
2011-4-15
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pubmed:abstractText |
A new switch-on fluorescent probe containing the natural product cryptolepine analogue benzofuroquinolinium moiety (binding scaffold) and a benzothiazole moiety (signalling unit) shows a remarkable fluorescence enhancement selective for the G-quadruplex nucleic acid structure. Binding studies revealed that the highly selective response of the fluorescent probe arises from end-stack binding to G-quadruplex.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1364-548X
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pubmed:author |
pubmed-author:AtaS ASA,
pubmed-author:ChanFung-YiFY,
pubmed-author:ChanPak-HoPH,
pubmed-author:ChungWai-HongWH,
pubmed-author:GuLian-QuanLQ,
pubmed-author:HuangZhi-ShuZS,
pubmed-author:LuYu-JingYJ,
pubmed-author:SunNingN,
pubmed-author:TonT VTV,
pubmed-author:WongKwok-YinKY,
pubmed-author:WongWing-LeungWL,
pubmed-author:YanSiu-CheongSC
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pubmed:copyrightInfo |
© The Royal Society of Chemistry 2011
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pubmed:issnType |
Electronic
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pubmed:day |
7
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pubmed:volume |
47
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
4971-3
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pubmed:meshHeading |
pubmed-meshheading:21431154-Benzothiazoles,
pubmed-meshheading:21431154-Binding Sites,
pubmed-meshheading:21431154-Cell Line, Tumor,
pubmed-meshheading:21431154-DNA,
pubmed-meshheading:21431154-Fluorescence,
pubmed-meshheading:21431154-Fluorescent Dyes,
pubmed-meshheading:21431154-G-Quadruplexes,
pubmed-meshheading:21431154-Humans,
pubmed-meshheading:21431154-Indole Alkaloids,
pubmed-meshheading:21431154-Intercalating Agents,
pubmed-meshheading:21431154-Microscopy, Fluorescence,
pubmed-meshheading:21431154-Models, Molecular,
pubmed-meshheading:21431154-Quinolines,
pubmed-meshheading:21431154-Quinolinium Compounds,
pubmed-meshheading:21431154-Spectrometry, Fluorescence
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pubmed:year |
2011
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pubmed:articleTitle |
Benzothiazole-substituted benzofuroquinolinium dye: a selective switch-on fluorescent probe for G-quadruplex.
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pubmed:affiliation |
Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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