rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
5
|
pubmed:dateCreated |
2011-4-8
|
pubmed:abstractText |
Serum and glucocorticoid regulated kinase 1 (SGK1) expression is increased by aldosterone and is a key regulator of the amiloride-sensitive sodium channel (ENaC) in the distal nephron. We have previously shown that two SNPs in SGK1 (rs1057293 and rs1743966) are associated with blood pressure variation and blood pressure progression in the general population. Therefore, we tested the association of these variants with ischaemic stroke.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
May
|
pubmed:issn |
1473-5598
|
pubmed:author |
|
pubmed:copyrightInfo |
© 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
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pubmed:issnType |
Electronic
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pubmed:volume |
29
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
884-9
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pubmed:dateRevised |
2011-11-2
|
pubmed:meshHeading |
pubmed-meshheading:21430556-Aged,
pubmed-meshheading:21430556-Aged, 80 and over,
pubmed-meshheading:21430556-Brain Ischemia,
pubmed-meshheading:21430556-Case-Control Studies,
pubmed-meshheading:21430556-Epithelial Sodium Channel,
pubmed-meshheading:21430556-Female,
pubmed-meshheading:21430556-Humans,
pubmed-meshheading:21430556-Immediate-Early Proteins,
pubmed-meshheading:21430556-Logistic Models,
pubmed-meshheading:21430556-Male,
pubmed-meshheading:21430556-Middle Aged,
pubmed-meshheading:21430556-Protein-Serine-Threonine Kinases,
pubmed-meshheading:21430556-Stroke
|
pubmed:year |
2011
|
pubmed:articleTitle |
Genetic variants in serum and glucocortocoid regulated kinase 1, a regulator of the epithelial sodium channel, are associated with ischaemic stroke.
|
pubmed:affiliation |
Clinical Research Center (CRC), Entrance 72, Bldg 91, Floor 12, Malmö University Hospital, SE 205 02 Malmö, Sweden.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|