Linked Life Data

21429781

Source:http://linkedlifedata.com/resource/pubmed/id/21429781

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2011-4-12
pubmed:abstractText
There is a two-way traffic of cells through the placenta during the pregnancy (feta and maternal microchimerisms). Fetal cells migrate in the maternal body where they are present long after birth. The fetal microchimerism may be deleterious for the mother when implicated in the induction of autoimmune diseases and of repeated abortion. Usually fetal microchimerism is beneficial for the mothers. Fetal cells can repair damaged tissues, transmit paternal resistance alleles, improve the directory of T cell receptors. In cancer, the effects are more contrasted, beneficial and protective for certain cancers, harmful and favouring the development for the others. The phenomenon of fetal and maternal microchimerisms inspires numerous questions and offers new perspectives on the biology of pregnancy and cancer, on pathogenesis of auto-immunity, of the transplantations, without forgetting the biology of the heredity because these cells could bring resistance or risk alleles for some diseases from the father towards the mother through the fetus, through the mother to the fetus, from the first fetus of a first pregnancy to the next fetus through the woman.
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1769-6682
pubmed:author
pubmed:copyrightInfo
Copyright © 2011 Elsevier Masson SAS. All rights reserved.
pubmed:issnType
Electronic
pubmed:volume
39
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
224-31
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
[Is fetal microchimerism beneficial for the fetus or the mother].
pubmed:affiliation
Laboratoire de neuro-immunologie et neurochimie évolutives, université Nord-de-France Lille, CNRS, MALDI Imaging Team, France.
pubmed:publicationType
Journal Article, English Abstract, Review