21425124

Source:http://linkedlifedata.com/resource/pubmed/id/21425124

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0021756, umls-concept:C0024141, umls-concept:C0314603, umls-concept:C0443211, umls-concept:C1280500, umls-concept:C1285573, umls-concept:C1328885, umls-concept:C1416406
pubmed:issue	6
pubmed:dateCreated	2011-6-1
pubmed:abstractText	Genetic association of the IL2/IL21 region at chromosome 4q27 has previously been reported in lupus and a number of autoimmune and inflammatory diseases. This study was undertaken to determine whether this genetic effect could be localized, using a very large cohort of lupus patients and controls.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/AI-024717, http://linkedlifedata.com/resource/pubmed/grant/AI-063274, http://linkedlifedata.com/resource/pubmed/grant/AI-31584, http://linkedlifedata.com/resource/pubmed/grant/AR-043274, http://linkedlifedata.com/resource/pubmed/grant/AR-048940, http://linkedlifedata.com/resource/pubmed/grant/AR-049084, http://linkedlifedata.com/resource/pubmed/grant/AR-42460, http://linkedlifedata.com/resource/pubmed/grant/AR-62277, http://linkedlifedata.com/resource/pubmed/grant/K24-AR-002138, http://linkedlifedata.com/resource/pubmed/grant/P20-RR-020143, http://linkedlifedata.com/resource/pubmed/grant/P30 RR031152-01, http://linkedlifedata.com/resource/pubmed/grant/P30-AR-053483, http://linkedlifedata.com/resource/pubmed/grant/P602-AR-30692, http://linkedlifedata.com/resource/pubmed/grant/R01 CA141700-01, http://linkedlifedata.com/resource/pubmed/grant/R01-AR-043727, http://linkedlifedata.com/resource/pubmed/grant/R03 AI076729-01, http://linkedlifedata.com/resource/pubmed/grant/R03 AI076729-02, http://linkedlifedata.com/resource/pubmed/grant/R03-AI-076729, http://linkedlifedata.com/resource/pubmed/grant/RC1 AR058621-01, http://linkedlifedata.com/resource/pubmed/grant/UL1-RR-025741
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/0370605
pubmed:citationSubset	AIM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-2, http://linkedlifedata.com/resource/pubmed/chemical/Interleukins, http://linkedlifedata.com/resource/pubmed/chemical/interleukin-21
pubmed:status	MEDLINE
pubmed:month	Jun
pubmed:issn	1529-0131
pubmed:author	pubmed-author:Alarcón-RiquelmeMarta EME, pubmed-author:AlarcónGraciela SGS, pubmed-author:BIOLUPUS Network, pubmed-author:BrownElizabeth EEE, pubmed-author:EdbergJeffrey CJC, pubmed-author:GaffneyPatrick MPM, pubmed-author:GilkesonGary SGS, pubmed-author:HarleyJohn BJB, pubmed-author:HughesTravisT, pubmed-author:JamesJudith AJA, pubmed-author:KaufmanKenneth MKM, pubmed-author:KellyJennifer AJA, pubmed-author:Kim-HowardXanaX, pubmed-author:KimberlyRobert PRP, pubmed-author:LangefeldCarl DCD, pubmed-author:MartínJavierJ, pubmed-author:MerrillJoan TJT, pubmed-author:MoserKathy LKL, pubmed-author:NathSwapan KSK, pubmed-author:PetriMichelleM, pubmed-author:Ramsey-GoldmanRosalindR, pubmed-author:ReveilleJohn DJD, pubmed-author:SanchezElenaE, pubmed-author:SawalhaAmr HAH, pubmed-author:ViláLuis MLM, pubmed-author:VyseTimothy JTJ, pubmed-author:ZieglerJulieJ
pubmed:copyrightInfo	Copyright © 2011 by the American College of Rheumatology.
pubmed:issnType	Electronic
pubmed:volume	63
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	1689-97
pubmed:dateRevised	2011-9-26
pubmed:meshHeading	pubmed-meshheading:21425124-African Continental Ancestry Group, pubmed-meshheading:21425124-Chromosome Mapping, pubmed-meshheading:21425124-Chromosomes, Human, Pair 4, pubmed-meshheading:21425124-Cohort Studies, pubmed-meshheading:21425124-European Continental Ancestry Group, pubmed-meshheading:21425124-Genetic Association Studies, pubmed-meshheading:21425124-Genetic Predisposition to Disease, pubmed-meshheading:21425124-Genotype, pubmed-meshheading:21425124-Humans, pubmed-meshheading:21425124-Interleukin-2, pubmed-meshheading:21425124-Interleukins, pubmed-meshheading:21425124-Lupus Erythematosus, Systemic, pubmed-meshheading:21425124-Polymorphism, Single Nucleotide
pubmed:year	2011
pubmed:articleTitle	Fine-mapping and transethnic genotyping establish IL2/IL21 genetic association with lupus and localize this genetic effect to IL21.
pubmed:affiliation	Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA.
pubmed:publicationType	Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural