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pubmed-article:21424008pubmed:abstractTextWe employed primer extension reactions to uncover folding motifs in a nuclease hypersensitive element (NHE) with a complex guanine pattern, located in the human KRAS promoter. We also identified and characterized a new G-rich motif of 21 nt capable of forming a parallel G-quadruplex that is disrupted by protein UP1.lld:pubmed
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pubmed-article:21424008pubmed:articleTitlePrimer extension reactions as a tool to uncover folding motifs within complex G-rich sequences: analysis of the human KRAS NHE.lld:pubmed
pubmed-article:21424008pubmed:affiliationDepartment of Medical and Biological Science, University of Udine, 33100 Udine, Italy.lld:pubmed
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