21423588

Source:http://linkedlifedata.com/resource/pubmed/id/21423588

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0011923, umls-concept:C0018026, umls-concept:C0021701, umls-concept:C0027651, umls-concept:C0087111, umls-concept:C1881983
pubmed:dateCreated	2011-3-22
pubmed:abstractText	Gold nanoshells (NSs) have already shown great promise as photothermal actuators for cancer therapy. Integrin ?v?3 is a marker that is specifically and preferentially overexpressed on multiple tumor types and on angiogenic tumor neovasculature. Active targeting of NSs to integrin ?v?3 offers the potential to increase accumulation preferentially in tumors and thereby enhance therapy efficacy.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/1R21CA133691, http://linkedlifedata.com/resource/pubmed/grant/R21 CA133691-01A2, http://linkedlifedata.com/resource/pubmed/grant/R21 CA133691-02
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pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/101263847
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Copper Radioisotopes, http://linkedlifedata.com/resource/pubmed/chemical/Gold, http://linkedlifedata.com/resource/pubmed/chemical/Integrin alphaVbeta3, http://linkedlifedata.com/resource/pubmed/chemical/Nanoconjugates, http://linkedlifedata.com/resource/pubmed/chemical/Peptides, Cyclic, http://linkedlifedata.com/resource/pubmed/chemical/cyclic...
pubmed:status	MEDLINE
pubmed:issn	1178-2013
pubmed:author	pubmed-author:BERGS SSS, pubmed-author:DeorukhkarAmit AAA, pubmed-author:DiagaradjaneParmeswaranP, pubmed-author:GoinsBethB, pubmed-author:KrishnanSunilS, pubmed-author:PhillipsWilliam TWT, pubmed-author:SchwartzJonJ, pubmed-author:WangZhengZ, pubmed-author:XieHuanH
pubmed:issnType	Electronic
pubmed:volume	6
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	259-69
pubmed:meshHeading	pubmed-meshheading:21423588-Animals, pubmed-meshheading:21423588-Carcinoma, Squamous Cell, pubmed-meshheading:21423588-Cell Line, Tumor, pubmed-meshheading:21423588-Copper Radioisotopes, pubmed-meshheading:21423588-Enzyme-Linked Immunosorbent Assay, pubmed-meshheading:21423588-Gold, pubmed-meshheading:21423588-Hot Temperature, pubmed-meshheading:21423588-Humans, pubmed-meshheading:21423588-Hyperthermia, Induced, pubmed-meshheading:21423588-Integrin alphaVbeta3, pubmed-meshheading:21423588-Laser Therapy, pubmed-meshheading:21423588-Mice, pubmed-meshheading:21423588-Mice, Nude, pubmed-meshheading:21423588-Models, Animal, pubmed-meshheading:21423588-Nanoconjugates, pubmed-meshheading:21423588-Nanoshells, pubmed-meshheading:21423588-Peptides, Cyclic, pubmed-meshheading:21423588-Protein Binding, pubmed-meshheading:21423588-Rats, pubmed-meshheading:21423588-Rats, Nude, pubmed-meshheading:21423588-Tissue Distribution, pubmed-meshheading:21423588-Tomography, Emission-Computed, pubmed-meshheading:21423588-Transplantation, Heterologous
pubmed:year	2011
pubmed:articleTitle	Integrin ?v?3-targeted gold nanoshells augment tumor vasculature-specific imaging and therapy.
pubmed:affiliation	Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, Texas Southern University, Houston, TX 77030, USA.
pubmed:publicationType	Journal Article, Comparative Study, Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't

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