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| pubmed-article:2142303 | lifeskim:mentions | umls-concept:C0027923 | lld:lifeskim |
| pubmed-article:2142303 | lifeskim:mentions | umls-concept:C0205147 | lld:lifeskim |
| pubmed-article:2142303 | pubmed:issue | 13 | lld:pubmed |
| pubmed-article:2142303 | pubmed:dateCreated | 1990-8-15 | lld:pubmed |
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| pubmed-article:2142303 | pubmed:abstractText | The mating-type locus of the haploid filamentous fungus Neurospora crassa is a regulatory region that controls entry into the sexual cycle and prevents formation of mixed mating-type heterokaryons in the vegetative phase. The locus consists of alternative sequences called A and a. The A mating-type DNA sequence of Neurospora crassa is composed of a region of 5301 base pairs that has little similarity to the sequence present at the mating-type locus in an a mating-type strain. However, the sequences flanking the mating-type locus in the A haploid and a haploid genome are essentially identical. The region of the A mating-type sequence required for expression of the heterokaryon incompatibility and sexual functions has been localized to a single open reading frame (ORF) encoding a polypeptide of 288 amino acids. Sequence analysis of sterile, heterokaryon-compatible mutants reveals frameshift mutations in this same ORF. The putative 288-amino acid product has a region of similarity to the MAT alpha 1 polypeptide of Saccharomyces cerevisiae. | lld:pubmed |
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| pubmed-article:2142303 | pubmed:language | eng | lld:pubmed |
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| pubmed-article:2142303 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:2142303 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2142303 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:2142303 | pubmed:issn | 0027-8424 | lld:pubmed |
| pubmed-article:2142303 | pubmed:author | pubmed-author:MetzenbergR... | lld:pubmed |
| pubmed-article:2142303 | pubmed:author | pubmed-author:GlassN LNL | lld:pubmed |
| pubmed-article:2142303 | pubmed:author | pubmed-author:Grotelueschen... | lld:pubmed |
| pubmed-article:2142303 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2142303 | pubmed:volume | 87 | lld:pubmed |
| pubmed-article:2142303 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2142303 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2142303 | pubmed:pagination | 4912-6 | lld:pubmed |
| pubmed-article:2142303 | pubmed:dateRevised | 2010-9-9 | lld:pubmed |
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| pubmed-article:2142303 | pubmed:year | 1990 | lld:pubmed |
| pubmed-article:2142303 | pubmed:articleTitle | Neurospora crassa A mating-type region. | lld:pubmed |
| pubmed-article:2142303 | pubmed:affiliation | Department of Physiological Chemistry, University of Wisconsin, Madison 53706. | lld:pubmed |
| pubmed-article:2142303 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2142303 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:2142303 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:2142303 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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