|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
13
|
|
pubmed:dateCreated |
1990-8-15
|
|
pubmed:databankReference |
|
|
pubmed:abstractText |
The mating-type locus of the haploid filamentous fungus Neurospora crassa is a regulatory region that controls entry into the sexual cycle and prevents formation of mixed mating-type heterokaryons in the vegetative phase. The locus consists of alternative sequences called A and a. The A mating-type DNA sequence of Neurospora crassa is composed of a region of 5301 base pairs that has little similarity to the sequence present at the mating-type locus in an a mating-type strain. However, the sequences flanking the mating-type locus in the A haploid and a haploid genome are essentially identical. The region of the A mating-type sequence required for expression of the heterokaryon incompatibility and sexual functions has been localized to a single open reading frame (ORF) encoding a polypeptide of 288 amino acids. Sequence analysis of sterile, heterokaryon-compatible mutants reveals frameshift mutations in this same ORF. The putative 288-amino acid product has a region of similarity to the MAT alpha 1 polypeptide of Saccharomyces cerevisiae.
|
|
pubmed:grant |
|
|
pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/2142303-140861,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2142303-17247122,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2142303-17248797,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2142303-2140508,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2142303-2142304,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2142303-2461560,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2142303-2550323,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2142303-271968,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2142303-2840740,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2142303-2942762,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2142303-3006051,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2142303-3070323,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2142303-327765,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2142303-3304657,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2142303-4504350,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2142303-5512565,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2142303-6246368,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2142303-6256655,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2142303-6256656,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2142303-6272290,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2142303-6276024,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2142303-6304321,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2142303-6337727,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2142303-6546423,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2142303-7034964
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jul
|
|
pubmed:issn |
0027-8424
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
87
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
4912-6
|
|
pubmed:dateRevised |
2010-9-9
|
|
pubmed:meshHeading |
pubmed-meshheading:2142303-Amino Acid Sequence,
pubmed-meshheading:2142303-Base Sequence,
pubmed-meshheading:2142303-Chromosome Deletion,
pubmed-meshheading:2142303-Cloning, Molecular,
pubmed-meshheading:2142303-Escherichia coli,
pubmed-meshheading:2142303-Gene Amplification,
pubmed-meshheading:2142303-Genes, Fungal,
pubmed-meshheading:2142303-Genes, Mating Type, Fungal,
pubmed-meshheading:2142303-Haploidy,
pubmed-meshheading:2142303-Molecular Sequence Data,
pubmed-meshheading:2142303-Neurospora,
pubmed-meshheading:2142303-Neurospora crassa,
pubmed-meshheading:2142303-Peptides,
pubmed-meshheading:2142303-Pheromones,
pubmed-meshheading:2142303-RNA, Fungal,
pubmed-meshheading:2142303-Sequence Homology, Nucleic Acid,
pubmed-meshheading:2142303-Spheroplasts,
pubmed-meshheading:2142303-Transformation, Genetic
|
|
pubmed:year |
1990
|
|
pubmed:articleTitle |
Neurospora crassa A mating-type region.
|
|
pubmed:affiliation |
Department of Physiological Chemistry, University of Wisconsin, Madison 53706.
|
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|
