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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2011-5-4
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pubmed:abstractText |
Low brain-derived neurotrophic factor (BDNF) levels are observed in both depressed and diabetes patients. Animal research has shown that omega-3 polyunsaturated fatty acids increase BDNF levels. In this exploratory randomized double-blind placebo-controlled study in diabetes patients with major depression, we tested whether (a) omega- 3 ethyl-eicosapentaenoic acid (E-EPA) leads to increased serum BDNF levels and (b) whether changes in BDNF levels are associated with corresponding changes in depression.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1423-0224
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pubmed:author |
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pubmed:copyrightInfo |
Copyright © 2011 S. Karger AG, Basel.
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pubmed:issnType |
Electronic
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pubmed:volume |
63
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
219-23
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pubmed:meshHeading |
pubmed-meshheading:21422768-Antidepressive Agents,
pubmed-meshheading:21422768-Brain-Derived Neurotrophic Factor,
pubmed-meshheading:21422768-Depressive Disorder, Major,
pubmed-meshheading:21422768-Diabetes Mellitus, Type 2,
pubmed-meshheading:21422768-Dietary Supplements,
pubmed-meshheading:21422768-Eicosapentaenoic Acid,
pubmed-meshheading:21422768-Female,
pubmed-meshheading:21422768-Humans,
pubmed-meshheading:21422768-Male,
pubmed-meshheading:21422768-Middle Aged,
pubmed-meshheading:21422768-Pilot Projects,
pubmed-meshheading:21422768-Severity of Illness Index
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pubmed:year |
2011
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pubmed:articleTitle |
Supplementation with eicosapentaenoic omega-3 fatty acid does not influence serum brain-derived neurotrophic factor in diabetes mellitus patients with major depression: a randomized controlled pilot study.
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pubmed:affiliation |
CoRPS-Center of Research on Psychology in Somatic Diseases, Department of Medical Psychology and Neuropsychology, Tilburg University, Tilburg, The Netherlands.
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
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