Source:http://linkedlifedata.com/resource/pubmed/id/21422220
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
2011-5-19
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pubmed:abstractText |
A novel gene cassette, aacA43, was identified in the aadB-aacA43-oxa10-smr2 cassette array in a class 1 integron. Like related aminoglycoside-(6')-acetyltransferases, AacA43 confers clinically relevant resistance to kanamycin, tobramycin, and some less-used aminoglycosides but not to gentamicin. Although transferable on an IncL/M plasmid, aacA43 was identified in only two different Klebsiella pneumoniae strains (14 isolates), one Escherichia coli strain (2 isolates), and one Enterobacter cloacae strain in a survey of patients in a Sydney intensive care unit in 2004-2005.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1098-6596
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
55
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2979-82
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pubmed:meshHeading |
pubmed-meshheading:21422220-Acetyltransferases,
pubmed-meshheading:21422220-Amino Acid Sequence,
pubmed-meshheading:21422220-Base Sequence,
pubmed-meshheading:21422220-Drug Resistance, Bacterial,
pubmed-meshheading:21422220-Enterobacter cloacae,
pubmed-meshheading:21422220-Escherichia coli,
pubmed-meshheading:21422220-Humans,
pubmed-meshheading:21422220-Integrons,
pubmed-meshheading:21422220-Klebsiella pneumoniae,
pubmed-meshheading:21422220-Molecular Sequence Data,
pubmed-meshheading:21422220-Plasmids,
pubmed-meshheading:21422220-Polymerase Chain Reaction
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pubmed:year |
2011
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pubmed:articleTitle |
A novel gene cassette, aacA43, in a plasmid-borne class 1 integron.
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pubmed:affiliation |
Centre for Infectious Diseases and Microbiology, Level 3, ICPMR Building, Westmead Hospital, Wentworthville, New South Wales 2145, Australia. sally.partridge@swahs.health.nsw.gov.au
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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