Source:http://linkedlifedata.com/resource/pubmed/id/21419785
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2011-6-6
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pubmed:abstractText |
We report a methodology for computing functional vascular density within a rodent dorsal window chamber model based on long-exposure laser speckle imaging (LSI). This technique relies on the presence of flow to create detailed vasculature maps. Employing this contrast mechanism is not possible using conventional imaging methods. Additionally, a freeware algorithm for computing functional vascular density (FVD) from images acquired using long-exposure LSI is also described to facilitate ease in adopting this method. We demonstrate that together these tools can be used to compute FVD nearly twelve times faster than manual computation, yet with comparable accuracy.
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pubmed:grant |
http://linkedlifedata.com/resource/pubmed/grant/P41 RR001192-30,
http://linkedlifedata.com/resource/pubmed/grant/P41 RR001192-31,
http://linkedlifedata.com/resource/pubmed/grant/P41 RR001192-32,
http://linkedlifedata.com/resource/pubmed/grant/R01 HD065536,
http://linkedlifedata.com/resource/pubmed/grant/R21 HL104203,
http://linkedlifedata.com/resource/pubmed/grant/R21 HL104203-02
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1095-9319
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pubmed:author | |
pubmed:copyrightInfo |
Copyright © 2011 Elsevier Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
82
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
92-5
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pubmed:meshHeading |
pubmed-meshheading:21419785-Algorithms,
pubmed-meshheading:21419785-Animals,
pubmed-meshheading:21419785-Image Processing, Computer-Assisted,
pubmed-meshheading:21419785-Laser-Doppler Flowmetry,
pubmed-meshheading:21419785-Mice,
pubmed-meshheading:21419785-Mice, Inbred Strains,
pubmed-meshheading:21419785-Microvessels,
pubmed-meshheading:21419785-Regional Blood Flow,
pubmed-meshheading:21419785-Skin
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pubmed:year |
2011
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pubmed:articleTitle |
Automated computation of functional vascular density using laser speckle imaging in a rodent window chamber model.
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pubmed:affiliation |
Department of Biomedical Engineering, University of California, Irvine, CA 92697, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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