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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2011-5-19
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pubmed:abstractText |
Circulating angiogenic cells (CACs) participate in neovascularization and arterial repair. Although high-density lipoprotein (HDL) is known to enhance the functional activity of CACs, the mechanisms underlying this regulation are poorly understood. Here, we examined the mechanism(s) by which reconstituted HDL (rHDL) affects CAC senescence.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/CRTC2 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Lipoproteins, HDL,
http://linkedlifedata.com/resource/pubmed/chemical/MTOR protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins c-akt,
http://linkedlifedata.com/resource/pubmed/chemical/Sirolimus,
http://linkedlifedata.com/resource/pubmed/chemical/TERT protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/TOR Serine-Threonine Kinases,
http://linkedlifedata.com/resource/pubmed/chemical/Telomerase,
http://linkedlifedata.com/resource/pubmed/chemical/Transcription Factors,
http://linkedlifedata.com/resource/pubmed/chemical/mTORC1 complex, human
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1524-4636
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
31
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1421-9
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pubmed:meshHeading |
pubmed-meshheading:21415389-Active Transport, Cell Nucleus,
pubmed-meshheading:21415389-Animals,
pubmed-meshheading:21415389-Cell Aging,
pubmed-meshheading:21415389-Cells, Cultured,
pubmed-meshheading:21415389-Humans,
pubmed-meshheading:21415389-Lipoproteins, HDL,
pubmed-meshheading:21415389-Male,
pubmed-meshheading:21415389-Mice,
pubmed-meshheading:21415389-Mice, Inbred C57BL,
pubmed-meshheading:21415389-Neovascularization, Physiologic,
pubmed-meshheading:21415389-Phosphorylation,
pubmed-meshheading:21415389-Proteins,
pubmed-meshheading:21415389-Proto-Oncogene Proteins c-akt,
pubmed-meshheading:21415389-Signal Transduction,
pubmed-meshheading:21415389-Sirolimus,
pubmed-meshheading:21415389-TOR Serine-Threonine Kinases,
pubmed-meshheading:21415389-Telomerase,
pubmed-meshheading:21415389-Transcription Factors
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pubmed:year |
2011
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pubmed:articleTitle |
mTOR complex 2 activation by reconstituted high-density lipoprotein prevents senescence in circulating angiogenic cells.
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pubmed:affiliation |
Department of Pathology, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing, People's Republic of China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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