Linked Life Data

21415216

Source:http://linkedlifedata.com/resource/pubmed/id/21415216

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
2011-4-18
pubmed:abstractText
EML4-ALK (echinoderm microtubule-associated protein-like 4 anaplastic lymphoma kinase) was recently identified as a transforming fusion gene in non-small cell lung cancer. The purpose of the present study was to characterize the mechanism of malignant transformation by EML4-ALK.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/Apoptosis Regulatory Proteins, http://linkedlifedata.com/resource/pubmed/chemical/BIRC5 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Bcl-2-like protein 11, http://linkedlifedata.com/resource/pubmed/chemical/EML4-ALK fusion protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Inhibitor of Apoptosis Proteins, http://linkedlifedata.com/resource/pubmed/chemical/MAPK1 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Membrane Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Mitogen-Activated Protein Kinase 1, http://linkedlifedata.com/resource/pubmed/chemical/NVP-TAE684, http://linkedlifedata.com/resource/pubmed/chemical/Oncogene Proteins, Fusion, http://linkedlifedata.com/resource/pubmed/chemical/Protein-Tyrosine Kinases, http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins c-akt, http://linkedlifedata.com/resource/pubmed/chemical/Pyrimidines, http://linkedlifedata.com/resource/pubmed/chemical/Receptor Protein-Tyrosine Kinases, http://linkedlifedata.com/resource/pubmed/chemical/STAT3 Transcription Factor, http://linkedlifedata.com/resource/pubmed/chemical/anaplastic lymphoma kinase, http://linkedlifedata.com/resource/pubmed/chemical/p80(NPM-ALK) protein
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1078-0432
pubmed:author
pubmed:copyrightInfo
©2011 AACR.
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
17
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2140-8
pubmed:meshHeading
pubmed-meshheading:21415216-Animals, pubmed-meshheading:21415216-Apoptosis, pubmed-meshheading:21415216-Apoptosis Regulatory Proteins, pubmed-meshheading:21415216-Cell Line, Tumor, pubmed-meshheading:21415216-Cell Proliferation, pubmed-meshheading:21415216-Cell Transformation, Neoplastic, pubmed-meshheading:21415216-Female, pubmed-meshheading:21415216-Humans, pubmed-meshheading:21415216-Immunoblotting, pubmed-meshheading:21415216-Inhibitor of Apoptosis Proteins, pubmed-meshheading:21415216-Lung Neoplasms, pubmed-meshheading:21415216-Membrane Proteins, pubmed-meshheading:21415216-Mice, pubmed-meshheading:21415216-Mice, Nude, pubmed-meshheading:21415216-Mitogen-Activated Protein Kinase 1, pubmed-meshheading:21415216-NIH 3T3 Cells, pubmed-meshheading:21415216-Neoplasms, Experimental, pubmed-meshheading:21415216-Oncogene Proteins, Fusion, pubmed-meshheading:21415216-Protein-Tyrosine Kinases, pubmed-meshheading:21415216-Proto-Oncogene Proteins, pubmed-meshheading:21415216-Proto-Oncogene Proteins c-akt, pubmed-meshheading:21415216-Pyrimidines, pubmed-meshheading:21415216-RNA Interference, pubmed-meshheading:21415216-Receptor Protein-Tyrosine Kinases, pubmed-meshheading:21415216-STAT3 Transcription Factor, pubmed-meshheading:21415216-Signal Transduction, pubmed-meshheading:21415216-Transfection
pubmed:year
2011
pubmed:articleTitle
Role of ERK-BIM and STAT3-survivin signaling pathways in ALK inhibitor-induced apoptosis in EML4-ALK-positive lung cancer.
pubmed:affiliation
Department of Medical Oncology, Kinki University Faculty of Medicine, Osaka, Japan.
pubmed:publicationType
Journal Article