Source:http://linkedlifedata.com/resource/pubmed/id/21414285
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2011-5-2
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pubmed:abstractText |
A total of 314 individual Echinostoma revolutum were collected at different locations and times from domestic ducks from Khon Kaen Province, Thailand and Vientiane Province, the Lao People's Democratic Republic (PDR). Genetic variation of these parasites was analyzed using multilocus enzyme electrophoresis at three polymorphic loci namely, glucose-6-phosphate dehydrogenase (G6pd), malic enzyme (Me) and peptidase valine-leucine (PepA). High levels of genetic variability were found within and between populations. Significant heterozygote deficiencies compared with the predictions under Hardy-Weinberg equilibrium were detected in populations from Thailand and the Lao PDR for all loci except G6pd-1. Significant genetic differentiation was observed between spatially separated populations from Thailand and the Lao PDR. This as also true for some samples collected at different times in Thailand. The variability found may be consistent with a Wahlund effect, genetic drift and/or other factors such as the population structure of snail hosts. Our data provide further insight into the process of genetic divergence within and among geographically and temporally isolated populations of E. revolutum, and potentially other medically important echinostomes in Southeast Asia.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1873-6254
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pubmed:author | |
pubmed:copyrightInfo |
Copyright © 2011 Elsevier B.V. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
118
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
105-9
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pubmed:meshHeading |
pubmed-meshheading:21414285-Aminopeptidases,
pubmed-meshheading:21414285-Animals,
pubmed-meshheading:21414285-Ducks,
pubmed-meshheading:21414285-Echinostoma,
pubmed-meshheading:21414285-Genetic Variation,
pubmed-meshheading:21414285-Glucosephosphate Dehydrogenase,
pubmed-meshheading:21414285-Helminth Proteins,
pubmed-meshheading:21414285-Laos,
pubmed-meshheading:21414285-Malate Dehydrogenase,
pubmed-meshheading:21414285-Phylogeography,
pubmed-meshheading:21414285-Thailand
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pubmed:year |
2011
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pubmed:articleTitle |
Spatial and temporal genetic variation of Echinostoma revolutum (Trematoda: Echinostomatidae) from Thailand and the Lao PDR.
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pubmed:affiliation |
Walai Rukhavej Botanical Research Institute, Mahasarakham University, Maha Sarakham, Thailand.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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