rdf:type |
|
lifeskim:mentions |
umls-concept:C0012155,
umls-concept:C0012860,
umls-concept:C0014912,
umls-concept:C0016157,
umls-concept:C0162638,
umls-concept:C0392756,
umls-concept:C0871261,
umls-concept:C1511660,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C1882628,
umls-concept:C2911692
|
pubmed:issue |
9
|
pubmed:dateCreated |
2011-9-9
|
pubmed:abstractText |
Dietary fish oil is associated with a decrease in colon cancer incidence: in part through a reduction in DNA adduct formation and an induction of colonocyte apoptosis. Estradiol (E(2)) has also been demonstrated to be protective against colon cancer incidence. Studies evaluating fish oil diets and DNA adduct formation in the colon have been conducted in male models without regard to possible interactions with E(2).
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Sep
|
pubmed:issn |
1573-2568
|
pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:volume |
56
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
2585-94
|
pubmed:meshHeading |
pubmed-meshheading:21409371-Animals,
pubmed-meshheading:21409371-Apoptosis,
pubmed-meshheading:21409371-Colon,
pubmed-meshheading:21409371-DNA Adducts,
pubmed-meshheading:21409371-DNA Damage,
pubmed-meshheading:21409371-Dietary Fats, Unsaturated,
pubmed-meshheading:21409371-Estradiol,
pubmed-meshheading:21409371-Female,
pubmed-meshheading:21409371-Fish Oils,
pubmed-meshheading:21409371-Guanosine,
pubmed-meshheading:21409371-Male,
pubmed-meshheading:21409371-Ovariectomy,
pubmed-meshheading:21409371-Rats,
pubmed-meshheading:21409371-Rats, Sprague-Dawley,
pubmed-meshheading:21409371-Up-Regulation
|
pubmed:year |
2011
|
pubmed:articleTitle |
Dietary fish oil reduces DNA adduct formation while estradiol upregulates apoptosis in response to DNA damage in the rat colon.
|
pubmed:affiliation |
Department of Nutrition and Food Science, Texas A&M University, 373 Olsen Blvd, 2253 TAMU, College Station, TX 77843, USA. carmstrong04@tamu.edu
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|