Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2011-5-2
pubmed:abstractText
In view of the high prevalence and the relevant impairment of patients with obstructive sleep apnoea syndrome (OSAS) lots of methods are offered which promise definitive cures for or relevant improvement of OSAS. This report summarises the efficacy of alternative treatment options in OSAS. An interdisciplinary European Respiratory Society task force evaluated the scientific literature according to the standards of evidence-based medicine. Evidence supports the use of mandibular advancement devices in mild to moderate OSAS. Maxillomandibular osteotomy seems to be as efficient as continuous positive airway pressure (CPAP) in patients who refuse conservative treatment. Distraction osteogenesis is usefully applied in congenital micrognathia or midface hypoplasia. There is a trend towards improvment after weight reduction. Positional therapy is clearly inferior to CPAP and long-term compliance is poor. Drugs, nasal dilators and apnoea triggered muscle stimulation cannot be recommended as effective treatments of OSAS at the moment. Nasal surgery, radiofrequency tonsil reduction, tongue base surgery, uvulopalatal flap, laser midline glossectomy, tongue suspension and genioglossus advancement cannot be recommended as single interventions. Uvulopalatopharyngoplasty, pillar implants and hyoid suspension should only be considered in selected patients and potential benefits should be weighed against the risk of long-term side-effects. Multilevel surgery is only a salvage procedure for OSA patients.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
1399-3003
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
37
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1000-28
pubmed:meshHeading
pubmed-meshheading:21406515-Adolescent, pubmed-meshheading:21406515-Adult, pubmed-meshheading:21406515-Aged, pubmed-meshheading:21406515-Aged, 80 and over, pubmed-meshheading:21406515-Child, pubmed-meshheading:21406515-Child, Preschool, pubmed-meshheading:21406515-Continuous Positive Airway Pressure, pubmed-meshheading:21406515-Female, pubmed-meshheading:21406515-Humans, pubmed-meshheading:21406515-Hyoid Bone, pubmed-meshheading:21406515-Male, pubmed-meshheading:21406515-Mandibular Advancement, pubmed-meshheading:21406515-Middle Aged, pubmed-meshheading:21406515-Nose, pubmed-meshheading:21406515-Osteogenesis, Distraction, pubmed-meshheading:21406515-Palate, pubmed-meshheading:21406515-Pharynx, pubmed-meshheading:21406515-Salvage Therapy, pubmed-meshheading:21406515-Severity of Illness Index, pubmed-meshheading:21406515-Sleep Apnea, Obstructive, pubmed-meshheading:21406515-Tongue, pubmed-meshheading:21406515-Young Adult
pubmed:year
2011
pubmed:articleTitle
Non-CPAP therapies in obstructive sleep apnoea.
pubmed:affiliation
Institute for Pneumology at the University Witten/Herdecke,Clinic for Pneumology and Allergology, Centre of Sleep Medicine and Respiratory Care, Bethanien Hospital, Solingen, Germany. randerath@klinik-bethanien.de
pubmed:publicationType
Journal Article, Practice Guideline