Source:http://linkedlifedata.com/resource/pubmed/id/21402291
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2011-3-15
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pubmed:abstractText |
Standard approaches to estimation of Markov models with data from randomized controlled trials tend either to make a judgment about which transition(s) treatments act on, or they assume that treatment has a separate effect on every transition. An alternative is to fit a series of models that assume that treatment acts on specific transitions. Investigators can then choose among alternative models using goodness-of-fit statistics. However, structural uncertainty about any chosen parameterization will remain and this may have implications for the resulting decision and the need for further research.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
1524-4733
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pubmed:author | |
pubmed:copyrightInfo |
Copyright © 2011 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
14
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
205-18
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pubmed:meshHeading |
pubmed-meshheading:21402291-Asthma,
pubmed-meshheading:21402291-Bayes Theorem,
pubmed-meshheading:21402291-Cost-Benefit Analysis,
pubmed-meshheading:21402291-Decision Making,
pubmed-meshheading:21402291-Humans,
pubmed-meshheading:21402291-Markov Chains,
pubmed-meshheading:21402291-Models, Theoretical,
pubmed-meshheading:21402291-Monte Carlo Method,
pubmed-meshheading:21402291-Outcome Assessment (Health Care),
pubmed-meshheading:21402291-Randomized Controlled Trials as Topic,
pubmed-meshheading:21402291-Uncertainty
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pubmed:articleTitle |
Model averaging in the presence of structural uncertainty about treatment effects: influence on treatment decision and expected value of information.
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pubmed:affiliation |
School of Social and Community-Based Medicine, University of Bristol, Bristol, UK. Malcolm.price@bristol.ac.uk
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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