Source:http://linkedlifedata.com/resource/pubmed/id/21401730
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
2011-5-3
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pubmed:abstractText |
Nowadays, most paediatric liver transplant recipients receive a split or other technical variant graft from adult deceased or live donors, because of a lack of available age- and size matched paediatric donors. Few data are available, especially for liver grafts obtained from very young children (<6 years). We analysed all paediatric liver transplantations between 1989 and 2009. Recipients were divided into five groups (1-5) depending on donor age (<1, ?1 to <6, ?6 to <16, ?16 to <45, ?45 years). Overall, 413 paediatric liver transplantations from deceased donors were performed; 1- and 5-year graft survival rates were 75%, 80%, 78%, 81%, 74% and 75%, 64%, 70%, 67%, 46%, and 1- and 5-year patient survival rates were 88%, 91%, 90%, 89%, 78% and 88%, 84%, 84%, 83%, 63% for groups 1-5, respectively, without significant difference. Eight children received organs from donors younger than 1 year and 45 children received organs from donors between 1 and 6 years of age. Overall, vascular complications occurred in 13.2% of patients receiving organs from donors younger than 6 years. Analysis of our data revealed that the usage of liver grafts from donors younger than 6 years is a safe procedure. The outcome was comparable with grafts from older donors with excellent graft and patient survival, even for donors younger than 1 year.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1432-2277
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pubmed:author | |
pubmed:copyrightInfo |
© 2011 The Authors. Transplant International © 2011 European Society for Organ Transplantation.
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pubmed:issnType |
Electronic
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pubmed:volume |
24
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
610-8
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pubmed:meshHeading |
pubmed-meshheading:21401730-Adolescent,
pubmed-meshheading:21401730-Adult,
pubmed-meshheading:21401730-Alagille Syndrome,
pubmed-meshheading:21401730-Child,
pubmed-meshheading:21401730-Child, Preschool,
pubmed-meshheading:21401730-Cholestasis, Intrahepatic,
pubmed-meshheading:21401730-Female,
pubmed-meshheading:21401730-Graft Survival,
pubmed-meshheading:21401730-Humans,
pubmed-meshheading:21401730-Infant,
pubmed-meshheading:21401730-Liver Failure, Acute,
pubmed-meshheading:21401730-Liver Transplantation,
pubmed-meshheading:21401730-Living Donors,
pubmed-meshheading:21401730-Male,
pubmed-meshheading:21401730-Middle Aged,
pubmed-meshheading:21401730-Tissue Donors,
pubmed-meshheading:21401730-Treatment Outcome
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pubmed:year |
2011
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pubmed:articleTitle |
Liver transplantation in children using organs from young paediatric donors.
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pubmed:affiliation |
Department of Hepatobiliary Surgery and Visceral Transplantation, University Medical Centre Hamburg-Eppendorf, Martinistrasse 52, Hamburg, Germany. utaherden@gmail.com
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pubmed:publicationType |
Journal Article
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