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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2011-4-18
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pubmed:abstractText |
Right ventricular dysfunction occurs after tetralogy of Fallot repair and may relate to greater myocardial vulnerability to ischemia-reperfusion injury in cyanotic patients. The inducible form of heat shock protein 70 (HSP-70i), a molecular chaperone, is upregulated in response to cellular stress and limits myocardial injury against ischemia-reperfusion. We evaluated the myocardial expression of HSP-70i and its relation to right ventricular function and clinical outcome in patients with tetralogy of Fallot undergoing corrective surgery.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1097-685X
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pubmed:author |
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pubmed:copyrightInfo |
Copyright © 2011 The American Association for Thoracic Surgery. Published by Mosby, Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
141
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1184-91
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pubmed:meshHeading |
pubmed-meshheading:21397265-Blood Gas Analysis,
pubmed-meshheading:21397265-Blotting, Western,
pubmed-meshheading:21397265-Cardiac Surgical Procedures,
pubmed-meshheading:21397265-Case-Control Studies,
pubmed-meshheading:21397265-Child, Preschool,
pubmed-meshheading:21397265-Cyanosis,
pubmed-meshheading:21397265-Echocardiography, Doppler,
pubmed-meshheading:21397265-Female,
pubmed-meshheading:21397265-HSP72 Heat-Shock Proteins,
pubmed-meshheading:21397265-Hemodynamics,
pubmed-meshheading:21397265-Humans,
pubmed-meshheading:21397265-Infant,
pubmed-meshheading:21397265-Male,
pubmed-meshheading:21397265-Myocardium,
pubmed-meshheading:21397265-Scotland,
pubmed-meshheading:21397265-Tetralogy of Fallot,
pubmed-meshheading:21397265-Time Factors,
pubmed-meshheading:21397265-Treatment Outcome,
pubmed-meshheading:21397265-Troponin I,
pubmed-meshheading:21397265-Up-Regulation,
pubmed-meshheading:21397265-Ventricular Dysfunction, Right,
pubmed-meshheading:21397265-Ventricular Function, Right
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pubmed:year |
2011
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pubmed:articleTitle |
Myocardial expression of heat shock protein 70i protects early postoperative right ventricular function in cyanotic tetralogy of Fallot.
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pubmed:affiliation |
Department of Cardiac Surgery, Royal Hospital for Sick Children, Yorkhill, Glasgow, United Kingdom.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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