21396644

Source:http://linkedlifedata.com/resource/pubmed/id/21396644

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0003483, umls-concept:C0014257, umls-concept:C0071097, umls-concept:C0087071, umls-concept:C0162638, umls-concept:C1292733, umls-concept:C1515877, umls-concept:C1879547
pubmed:issue	1
pubmed:dateCreated	2011-5-6
pubmed:abstractText	Telomeres and associated proteins are regulators of cellular survival, regeneration and aging. PPAR-? agonists may mediate vascular effects in addition to insulin sensitizing. We therefore examined whether pioglitazone regulates vascular telomere biology.
pubmed:commentsCorrections	http://linkedlifedata.com/resource/pubmed/commentcorrection/21396644-21411087
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/0242543
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/CDC2 Protein Kinase, http://linkedlifedata.com/resource/pubmed/chemical/Cdkn2a protein, mouse, http://linkedlifedata.com/resource/pubmed/chemical/Cyclin-Dependent Kinase Inhibitor..., http://linkedlifedata.com/resource/pubmed/chemical/Lipopolysaccharides, http://linkedlifedata.com/resource/pubmed/chemical/Oxidants, http://linkedlifedata.com/resource/pubmed/chemical/PPAR gamma, http://linkedlifedata.com/resource/pubmed/chemical/Protein Kinase Inhibitors, http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins c-akt, http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger, http://linkedlifedata.com/resource/pubmed/chemical/TERT protein, human, http://linkedlifedata.com/resource/pubmed/chemical/TRF2 protein, mouse, http://linkedlifedata.com/resource/pubmed/chemical/Telomerase, http://linkedlifedata.com/resource/pubmed/chemical/Telomeric Repeat Binding Protein 2, http://linkedlifedata.com/resource/pubmed/chemical/Tert protein, mouse, http://linkedlifedata.com/resource/pubmed/chemical/Thiazolidinediones, http://linkedlifedata.com/resource/pubmed/chemical/Tumor Suppressor Protein p53, http://linkedlifedata.com/resource/pubmed/chemical/pioglitazone
pubmed:status	MEDLINE
pubmed:month	May
pubmed:issn	1879-1484
pubmed:author	pubmed-author:BöhmMichaelM, pubmed-author:GenschChristophC, pubmed-author:HaendelerJudithJ, pubmed-author:LaufsUlrichU, pubmed-author:PössJanineJ, pubmed-author:WernerChristianC
pubmed:copyrightInfo	Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.
pubmed:issnType	Electronic
pubmed:volume	216
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	23-34
pubmed:meshHeading	pubmed-meshheading:21396644-Animals, pubmed-meshheading:21396644-Aorta, pubmed-meshheading:21396644-Apoptosis, pubmed-meshheading:21396644-CDC2 Protein Kinase, pubmed-meshheading:21396644-Cattle, pubmed-meshheading:21396644-Cell Aging, pubmed-meshheading:21396644-Cell Survival, pubmed-meshheading:21396644-Cells, Cultured, pubmed-meshheading:21396644-Cyclin-Dependent Kinase Inhibitor p16, pubmed-meshheading:21396644-Cytoprotection, pubmed-meshheading:21396644-Endothelial Cells, pubmed-meshheading:21396644-Enzyme Activation, pubmed-meshheading:21396644-Humans, pubmed-meshheading:21396644-Leukocytes, Mononuclear, pubmed-meshheading:21396644-Lipopolysaccharides, pubmed-meshheading:21396644-Male, pubmed-meshheading:21396644-Mice, pubmed-meshheading:21396644-Mice, Inbred C57BL, pubmed-meshheading:21396644-Mice, Knockout, pubmed-meshheading:21396644-Oxidants, pubmed-meshheading:21396644-Oxidative Stress, pubmed-meshheading:21396644-PPAR gamma, pubmed-meshheading:21396644-Phosphorylation, pubmed-meshheading:21396644-Protein Kinase Inhibitors, pubmed-meshheading:21396644-Proto-Oncogene Proteins c-akt, pubmed-meshheading:21396644-RNA, Messenger, pubmed-meshheading:21396644-Telomerase, pubmed-meshheading:21396644-Telomere, pubmed-meshheading:21396644-Telomeric Repeat Binding Protein 2, pubmed-meshheading:21396644-Thiazolidinediones, pubmed-meshheading:21396644-Time Factors, pubmed-meshheading:21396644-Tumor Suppressor Protein p53, pubmed-meshheading:21396644-Ultraviolet Rays
pubmed:year	2011
pubmed:articleTitle	Pioglitazone activates aortic telomerase and prevents stress-induced endothelial apoptosis.
pubmed:affiliation	Klinik für Innere Medizin III, Kardiologie, Angiologie und Internistische Intensivmedizin, Universitätsklinikum des Saarlandes, 66421 Homburg, Saar, Germany.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't