Source:http://linkedlifedata.com/resource/pubmed/id/21388718
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
2011-3-28
|
pubmed:abstractText |
A series of new 5,6-dihydro-indolo[1,2-a]quinoxaline derivatives has been prepared in moderate to excellent yields from 2-(indol-1-yl)phenylamines with aromatic aldehydes by an efficient and economical iron-catalyzed Pictet-Spengler reaction. Meanwhile, as compared with hymexazol, a commercially available agricultural fungicide at the concentration of 50 ?g/mL, some 5,6-dihydro-indolo[1,2-a]quinoxalines exhibited promising antifungal activities in vitro against the phytopathogenic fungi, and might be considered as novel promising lead candidates for further design and synthesis of agricultural fungicides.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
May
|
pubmed:issn |
1768-3254
|
pubmed:author | |
pubmed:copyrightInfo |
Copyright © 2011 Elsevier Masson SAS. All rights reserved.
|
pubmed:issnType |
Electronic
|
pubmed:volume |
46
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1919-25
|
pubmed:meshHeading |
pubmed-meshheading:21388718-Antifungal Agents,
pubmed-meshheading:21388718-Dose-Response Relationship, Drug,
pubmed-meshheading:21388718-Drug Design,
pubmed-meshheading:21388718-Fungi,
pubmed-meshheading:21388718-Indoles,
pubmed-meshheading:21388718-Microbial Sensitivity Tests,
pubmed-meshheading:21388718-Molecular Structure,
pubmed-meshheading:21388718-Quinoxalines,
pubmed-meshheading:21388718-Stereoisomerism
|
pubmed:year |
2011
|
pubmed:articleTitle |
Synthesis and antifungal activities of novel 5,6-dihydro-indolo[1,2-a]quinoxaline derivatives.
|
pubmed:affiliation |
Laboratory of Pharmaceutical Design and Synthesis, College of Sciences, Xinong Road 22#, Northwest A&F University, Yangling 712100, China. orgxuhui@nwsuaf.edu.cn
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|