Linked Life Data

21386770

Source:http://linkedlifedata.com/resource/pubmed/id/21386770

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
2011-3-25
pubmed:abstractText
Because CD4CD25Foxp3 regulatory T cells (Tregs) are essential for the maintenance of self-tolerance, significant interest surrounds the developmental cues for thymic-derived natural Tregs (nTregs) and periphery-generated adaptive Tregs (aTregs). In the transplant setting, the allograft may play a role in the generation of alloantigen-specific Tregs, but this role remains undefined. We examined whether the immune response to a transplant allograft results in the peripheral generation of aTregs.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1534-6080
pubmed:author
pubmed:issnType
Electronic
pubmed:day
15
pubmed:volume
91
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
707-13
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
Generation of adaptive regulatory T cells by alloantigen is required for some but not all transplant tolerance protocols.
pubmed:affiliation
Department of Surgery, Harvard Medical School, Massachusetts General Hospital, Boston, MA 02114, USA. jkim35@partners.org
pubmed:publicationType
Journal Article, Research Support, N.I.H., Extramural