pubmed-article:21385406 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:21385406 | lifeskim:mentions | umls-concept:C0011854 | lld:lifeskim |
pubmed-article:21385406 | lifeskim:mentions | umls-concept:C0004358 | lld:lifeskim |
pubmed-article:21385406 | lifeskim:mentions | umls-concept:C0061472 | lld:lifeskim |
pubmed-article:21385406 | lifeskim:mentions | umls-concept:C0162772 | lld:lifeskim |
pubmed-article:21385406 | lifeskim:mentions | umls-concept:C0009566 | lld:lifeskim |
pubmed-article:21385406 | lifeskim:mentions | umls-concept:C1511790 | lld:lifeskim |
pubmed-article:21385406 | lifeskim:mentions | umls-concept:C0332281 | lld:lifeskim |
pubmed-article:21385406 | lifeskim:mentions | umls-concept:C0205349 | lld:lifeskim |
pubmed-article:21385406 | pubmed:dateCreated | 2011-3-24 | lld:pubmed |
pubmed-article:21385406 | pubmed:abstractText | Autoantibodies against glutamate decarboxylase-65 (GAD??Abs) are thought to be a major immunological tool involved in pathogenic autoimmunity development in various diseases. GAD??Abs are a sensitive and specific marker for type 1 diabetes (T1D). These autoantibodies can also be found in 6-10% of patients classified with type 2 diabetes (T2D), as well as in 1-2% of the healthy population. The latter individuals are at low risk of developing T1D because the prevalence rate of GAD??Abs is only about 0.3%. It has, therefore, been suggested that the antibody binding to GAD?? in these three different GAD??Ab-positive phenotypes differ with respect to epitope specificity. The specificity of reactive oxygen species modified GAD?? (ROS-GAD??) is already well established in the T1D. However, its association in secondary complications of T1D has not yet been ascertained. Hence this study focuses on identification of autoantibodies against ROS-GAD?? (ROS-GAD??Abs) and quantitative assays in T1D associated complications. | lld:pubmed |
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pubmed-article:21385406 | pubmed:language | eng | lld:pubmed |
pubmed-article:21385406 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:21385406 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:21385406 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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pubmed-article:21385406 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:21385406 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:21385406 | pubmed:issn | 1471-2172 | lld:pubmed |
pubmed-article:21385406 | pubmed:author | pubmed-author:KhanMohd... | lld:pubmed |
pubmed-article:21385406 | pubmed:author | pubmed-author:KhanWahid... | lld:pubmed |
pubmed-article:21385406 | pubmed:author | pubmed-author:BangaKamalpre... | lld:pubmed |
pubmed-article:21385406 | pubmed:author | pubmed-author:MashalSubhash... | lld:pubmed |
pubmed-article:21385406 | pubmed:issnType | Electronic | lld:pubmed |
pubmed-article:21385406 | pubmed:volume | 12 | lld:pubmed |
pubmed-article:21385406 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:21385406 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:21385406 | pubmed:pagination | 19 | lld:pubmed |
pubmed-article:21385406 | pubmed:dateRevised | 2011-7-27 | lld:pubmed |
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pubmed-article:21385406 | pubmed:meshHeading | pubmed-meshheading:21385406... | lld:pubmed |
pubmed-article:21385406 | pubmed:year | 2011 | lld:pubmed |
pubmed-article:21385406 | pubmed:articleTitle | Detection of autoantibodies against reactive oxygen species modified glutamic acid decarboxylase-65 in type 1 diabetes associated complications. | lld:pubmed |
pubmed-article:21385406 | pubmed:affiliation | Department of Biochemistry, Faculty of Medicine and Health Sciences-Gomail, University of Aljabal Algharbil, Zawia-16418, Libya. wajidkhan11@gmail.com | lld:pubmed |
pubmed-article:21385406 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:21385406 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
entrez-gene:2572 | entrezgene:pubmed | pubmed-article:21385406 | lld:entrezgene |
http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:21385406 | lld:entrezgene |