rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2011-3-17
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pubmed:abstractText |
The association of CYP3A5, CYP3A4, and ABCB1 single nucleotide polymorphisms (SNPs) with cyclosporine (CsA) pharmacokinetics is controversial. The authors studied the influence of these SNPs on CsA pharmacokinetics as well as on the incidence of biopsy-proven acute rejection (BPAR) and renal function after kidney transplantation.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/ABCB1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/CYP3A4 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/CYP3A5 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Creatinine,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclosporine,
http://linkedlifedata.com/resource/pubmed/chemical/Cytochrome P-450 CYP3A,
http://linkedlifedata.com/resource/pubmed/chemical/Glucocorticoids,
http://linkedlifedata.com/resource/pubmed/chemical/Immunosuppressive Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Mycophenolic Acid,
http://linkedlifedata.com/resource/pubmed/chemical/P-Glycoprotein,
http://linkedlifedata.com/resource/pubmed/chemical/mycophenolate mofetil
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1536-3694
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pubmed:author |
|
pubmed:issnType |
Electronic
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pubmed:volume |
33
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
178-84
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pubmed:dateRevised |
2011-10-31
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pubmed:meshHeading |
pubmed-meshheading:21383650-Creatinine,
pubmed-meshheading:21383650-Cyclosporine,
pubmed-meshheading:21383650-Cytochrome P-450 CYP3A,
pubmed-meshheading:21383650-Delayed Graft Function,
pubmed-meshheading:21383650-Female,
pubmed-meshheading:21383650-Genotype,
pubmed-meshheading:21383650-Glucocorticoids,
pubmed-meshheading:21383650-Graft Rejection,
pubmed-meshheading:21383650-Humans,
pubmed-meshheading:21383650-Immunosuppressive Agents,
pubmed-meshheading:21383650-Internationality,
pubmed-meshheading:21383650-Kidney Transplantation,
pubmed-meshheading:21383650-Male,
pubmed-meshheading:21383650-Mycophenolic Acid,
pubmed-meshheading:21383650-P-Glycoprotein,
pubmed-meshheading:21383650-Polymorphism, Single Nucleotide,
pubmed-meshheading:21383650-Treatment Outcome
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pubmed:year |
2011
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pubmed:articleTitle |
Polymorphisms in CYP3A5, CYP3A4, and ABCB1 are not associated with cyclosporine pharmacokinetics nor with cyclosporine clinical end points after renal transplantation.
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pubmed:affiliation |
Department of Hospital Pharmacy, Clinical Pharmacology Unit, Erasmus MC, Rotterdam, The Netherlands. r.bouamar@erasmusmc.nl
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Multicenter Study
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