Switch to
Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1990-4-11
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pubmed:abstractText |
A double-blind crossover study was performed to evaluate the bronchodilating effect of different single doses of procaterol (less than 0.5 micrograms/kg, 1.5 micrograms/kg, and placebo) orally administered. Sixteen asthmatic children, age 6-12 years, participated in the trial. Pulmonary function, heart rate, blood pressure, and tremor were evaluated at 30, 60, 90, and 120 min and then hourly for 8 hours after administration. All three doses were therapeutically effective. The 1.5 micrograms/kg dose produced a more sustained bronchodilatation effect, but was also associated with an increase in the incidence of tremors. The 0.5 micrograms/kg dosage may, however, be a good starting dose because it assures a reasonable risk/benefit ratio.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0277-0903
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
27
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
21-30
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:2137815-Administration, Oral,
pubmed-meshheading:2137815-Asthma,
pubmed-meshheading:2137815-Bronchodilator Agents,
pubmed-meshheading:2137815-Child,
pubmed-meshheading:2137815-Dose-Response Relationship, Drug,
pubmed-meshheading:2137815-Drug Administration Schedule,
pubmed-meshheading:2137815-Ethanolamines,
pubmed-meshheading:2137815-Forced Expiratory Volume,
pubmed-meshheading:2137815-Heart Rate,
pubmed-meshheading:2137815-Humans,
pubmed-meshheading:2137815-Maximal Midexpiratory Flow Rate,
pubmed-meshheading:2137815-Procaterol,
pubmed-meshheading:2137815-Time Factors,
pubmed-meshheading:2137815-Tremor,
pubmed-meshheading:2137815-Vital Capacity
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pubmed:year |
1990
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pubmed:articleTitle |
Efficacy and duration of action of oral procaterol in asthmatic children after single administration of different dosages.
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pubmed:affiliation |
Policlinico Borgo Roma, Verona, Italy.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Controlled Clinical Trial
|