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pubmed:abstractText |
Cyclooxygenase2 (COX-2), one isoform of cyclooxygenase proinflammatory enzymes, is responsible for tumor development, invasion and metastasis. Due to its role and frequent overexpression in a variety of human malignancies, including osteosarcoma, COX-2 has received considerable attention. However, the function of COX-2 in the pathogenesis of cancer is not well understood. We examined the role of COX-2 in osteosarcoma.
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pubmed:affiliation |
Department of Orthopaedics, Affiliated First People's Hospital, Shanghai Jiao Tong University, 100 Haining Road, Shanghai 200080, China.
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