Linked Life Data

2137435

Source:http://linkedlifedata.com/resource/pubmed/id/2137435

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1990-3-27
pubmed:abstractText
The influence of cholinergic receptor blockade on the impedance of the respiratory system was studied in 10 healthy volunteers in a frequency spectrum between 4 and 52 Hz by means of the forced pseudo random-noise oscillation technique. Ipratropium bromide was used in the inhaled form in two doses (0.040 and 0.200 mg). Both does caused a significant decrease in oscillatory airway resistance, Rrs. No dose effect on Rrs was found. Both doses caused an increase in the reactance of the respiratory system, Xrs. This increase in Xrs was significantly greater after the inhalation of the higher dose. The effect of both doses on the real part of impedance can be explained by a dilation of the central airways. Furthermore, inhaled ipratropium bromide, especially in the higher dose, led to an increase in the imaginary part of impedance suggesting a decrease in the capacitance of pulmonary structures in normal subjects.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0174-4879
pubmed:author
pubmed:issnType
Print
pubmed:volume
28
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
33-8
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Dose effects of inhaled ipratropium bromide on the impedance of the respiratory system in normal subjects.
pubmed:affiliation
Department of Pulmonary Diseases, State University Limburg, Maastricht, The Netherlands.
pubmed:publicationType
Journal Article, Clinical Trial, Controlled Clinical Trial