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rdf:type |
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lifeskim:mentions |
umls-concept:C0003241,
umls-concept:C0007600,
umls-concept:C0021083,
umls-concept:C0086418,
umls-concept:C0205225,
umls-concept:C0205250,
umls-concept:C0302592,
umls-concept:C0332324,
umls-concept:C1514559,
umls-concept:C1518174,
umls-concept:C1704265
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pubmed:issue |
9
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pubmed:dateCreated |
2011-3-3
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|
pubmed:abstractText |
Epithelial cell adhesion molecule (EpCAM) is a surface glycoprotein highly differentially expressed in many epithelial malignancies. The goal of this study was to evaluate the expression of EpCAM and the potential of MT201 (adecatumumab), a human monoclonal antibody targeting EpCAM, against multiple primary cervical carcinoma cell lines.
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pubmed:grant |
|
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1525-1438
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|
pubmed:author |
pubmed-author:AzodiMasoudM,
pubmed-author:BelloneMartaM,
pubmed-author:BelloneStefaniaS,
pubmed-author:CasagrandeFrancescaF,
pubmed-author:CoccoEmilianoE,
pubmed-author:PecorelliSergioS,
pubmed-author:RüttingerDominikD,
pubmed-author:RichterChristine ECE,
pubmed-author:RutherfordThomas JTJ,
pubmed-author:SantinAlessandro DAD,
pubmed-author:SchwartzPeter EPE,
pubmed-author:SilasiDan-ArinDA,
pubmed-author:TodeschiniPaolaP
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pubmed:issnType |
Electronic
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pubmed:volume |
20
|
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1440-7
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pubmed:dateRevised |
2011-10-28
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pubmed:meshHeading |
pubmed-meshheading:21370592-Adult,
pubmed-meshheading:21370592-Aged,
pubmed-meshheading:21370592-Antibodies, Monoclonal,
pubmed-meshheading:21370592-Antigens, Neoplasm,
pubmed-meshheading:21370592-Carcinoma,
pubmed-meshheading:21370592-Cell Adhesion Molecules,
pubmed-meshheading:21370592-Cell Culture Techniques,
pubmed-meshheading:21370592-Cell Line, Tumor,
pubmed-meshheading:21370592-Female,
pubmed-meshheading:21370592-Flow Cytometry,
pubmed-meshheading:21370592-Gene Expression Profiling,
pubmed-meshheading:21370592-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:21370592-Humans,
pubmed-meshheading:21370592-Immunotherapy,
pubmed-meshheading:21370592-Middle Aged,
pubmed-meshheading:21370592-Treatment Outcome,
pubmed-meshheading:21370592-Uterine Cervical Neoplasms,
pubmed-meshheading:21370592-Young Adult
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pubmed:year |
2010
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|
pubmed:articleTitle |
Primary cervical carcinoma cell lines overexpress epithelial cell adhesion molecule (EpCAM) and are highly sensitive to immunotherapy with MT201, a fully human monoclonal anti-EpCAM antibody.
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pubmed:affiliation |
Division of Gynecologic Oncology, Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520-8063, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Evaluation Studies,
Research Support, N.I.H., Extramural
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