Linked Life Data

21368465

Source:http://linkedlifedata.com/resource/pubmed/id/21368465

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2011-3-3
pubmed:abstractText
A 78-year-old woman diagnosed with left breast cancer (T2N1M0, Stage II B) was given breast-conserving therapy with axillary dissection. Pathological findings of the tumor were: 2.5 cm in size, invasive ductal carcinoma, nuclear grade 3, positive lymphatic invasion and pN1a. ER and PgR were both positive, and HER2 was negative. Administration of anastrozole (1 mg/day) and UFT (300 mg/day) was performed as adjuvant therapy for 8 months. However, several subcutaneous nodules appeared in the left breast and left axilla, after 11 months. Cytology and histology of nodules indicated metastatic invasive ductal carcinoma. We began high-dose toremifene therapy (120 mg/day) (HD-TOR) for treatment of recurrence and complete remission (CR), and was obtained after 8 months in all recurrent lesions. In this study, we demonstrated a case of aromatase inhibitor-tolerant metastatic breast cancer revealing CR following high-dose toremifene therapy.
pubmed:language
jpn
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0385-0684
pubmed:author
pubmed:issnType
Print
pubmed:volume
38
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
93-6
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
[A case of aromatase inhibitor-tolerant metastatic breast cancer revealing complete remission with high-dose toremifene therapy].
pubmed:affiliation
Dept. of Breast Surgery, Maebashi Red Cross Hospital, Japan.
pubmed:publicationType
Journal Article, English Abstract, Case Reports