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rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
6
|
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pubmed:dateCreated |
2011-3-3
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|
pubmed:abstractText |
The widely used 23-valent plain polysaccharide vaccine (23vP) has limited effectiveness, produces short-lived immune responses, and induces attenuated antibody production after subsequent challenge with pneumococcal vaccines. Our goal was to examine whether priming with the 7-valent pneumococcal conjugate vaccine (PCV7) could enhance the immunogenicity of 23vP for the PCV7 serotypes and to investigate whether 23vP induced hyporesponsiveness could be overcome using PCV7.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1537-6591
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pubmed:author |
pubmed-author:AngusBrianB,
pubmed-author:BatemanElizabeth AEA,
pubmed-author:BeverleyPeter CPC,
pubmed-author:BowmanJaclynJ,
pubmed-author:ClutterbuckElizabethE,
pubmed-author:DiggleLindaL,
pubmed-author:LazarusRajekaR,
pubmed-author:MantDavidD,
pubmed-author:PetoTim ETE,
pubmed-author:PollardAndrew JAJ,
pubmed-author:YuLy-MeeLM
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pubmed:issnType |
Electronic
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|
pubmed:day |
15
|
|
pubmed:volume |
52
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
736-42
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pubmed:dateRevised |
2011-7-21
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pubmed:meshHeading |
pubmed-meshheading:21367726-Aged,
pubmed-meshheading:21367726-Antibodies, Bacterial,
pubmed-meshheading:21367726-Female,
pubmed-meshheading:21367726-Humans,
pubmed-meshheading:21367726-Immunization, Secondary,
pubmed-meshheading:21367726-Immunization Schedule,
pubmed-meshheading:21367726-Injections, Intramuscular,
pubmed-meshheading:21367726-Male,
pubmed-meshheading:21367726-Middle Aged,
pubmed-meshheading:21367726-Pneumococcal Vaccines,
pubmed-meshheading:21367726-Vaccination
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|
pubmed:year |
2011
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|
pubmed:articleTitle |
A randomized study comparing combined pneumococcal conjugate and polysaccharide vaccination schedules in adults.
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|
pubmed:affiliation |
Oxford Vaccine Group, University of Oxford, Oxford, UK. rajeka.lazarus@doctors.net.uk
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
|
