Source:http://linkedlifedata.com/resource/pubmed/id/21367440
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2011-3-28
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pubmed:abstractText |
Evaluating the performance of well child clinics on adherence to recommended perinatal hepatitis B prevention programmes as well as assessing the outcome of infants living with hepatitis B surface antigen (HBsAg)-positive parents is important. A retrospective study was performed of 336 babies who had at least one HBsAg-positive parent and were followed-up in the well child clinic of Gazi University Hospital (Ankara, Turkey) between 2001 and 2009. Rates of passive immunisation in 109 babies with HBsAg-positive mothers and initiation of hepatitis B vaccination of all 336 babies with HBsAg-positive parents were 98.8% and 100% respectively. Ninety-two babies (27.4%) were lost to follow-up before completing primary immunisation. The recommended perinatal hepatitis B prevention programme was performed successfully in 194 of the 306 infants who were old enough for post-vaccination serotesting (63.4%). One baby became HBsAg-positive, and 88.1% of babies were seroprotected. Hepatitis B surface antibody (anti-HBs) levels were found to be increased if the HBsAg-positive parent was the father. There was a negative correlation between serotesting time and anti-HBs titres. The study infants had a total of 187 siblings and 123 (65.8%) were serotested after completing primary immunisation with 108 found to be seropositive. Although the vaccination rate in the perinatal hepatitis B prevention programme is satisfactory, post-vaccination serotesting and evaluation of infants and their siblings are still deficient.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1878-3503
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pubmed:author | |
pubmed:copyrightInfo |
Copyright © 2010 Royal Society of Tropical Medicine and Hygiene. Published by Elsevier Ltd. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
105
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
220-5
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pubmed:meshHeading |
pubmed-meshheading:21367440-Carrier State,
pubmed-meshheading:21367440-Female,
pubmed-meshheading:21367440-Follow-Up Studies,
pubmed-meshheading:21367440-Guideline Adherence,
pubmed-meshheading:21367440-Hepatitis B,
pubmed-meshheading:21367440-Hepatitis B Surface Antigens,
pubmed-meshheading:21367440-Hepatitis B Vaccines,
pubmed-meshheading:21367440-Humans,
pubmed-meshheading:21367440-Infant,
pubmed-meshheading:21367440-Infectious Disease Transmission, Vertical,
pubmed-meshheading:21367440-Male,
pubmed-meshheading:21367440-Parents,
pubmed-meshheading:21367440-Practice Guidelines as Topic,
pubmed-meshheading:21367440-Retrospective Studies,
pubmed-meshheading:21367440-Turkey
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pubmed:year |
2011
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pubmed:articleTitle |
Evaluation of perinatal and intrafamilial hepatitis B prevention programmes in a well child clinic: 9-year follow-up study in Turkey.
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pubmed:affiliation |
Mersin University School of Medicine, Department of Social Pediatrics, Zeytinlibahce, Mersin, 33079, Turkey. seldapolat2003@hotmail.com
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pubmed:publicationType |
Journal Article
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