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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2011-3-2
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pubmed:abstractText |
Susceptibility to coronary artery disease (CAD) and diabetes is encoded by distinct, tightly-linked single nucleotide polymorphisms on chromosome 9p21. This study aimed to examine the association of variant rs1333049 on chromosome 9p21.3 with early-onset and severity of CAD in Chinese patients with and without type 2 diabetes, and to determine the possible impact of rs1333049 on glucose metabolism and inflammation pathways.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0366-6999
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
124
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
66-71
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pubmed:meshHeading |
pubmed-meshheading:21362310-Aged,
pubmed-meshheading:21362310-C-Reactive Protein,
pubmed-meshheading:21362310-Chromosomes, Human, Pair 9,
pubmed-meshheading:21362310-Coronary Angiography,
pubmed-meshheading:21362310-Coronary Artery Disease,
pubmed-meshheading:21362310-Diabetes Mellitus, Type 2,
pubmed-meshheading:21362310-Female,
pubmed-meshheading:21362310-Genetic Predisposition to Disease,
pubmed-meshheading:21362310-Genotype,
pubmed-meshheading:21362310-Hemoglobin A, Glycosylated,
pubmed-meshheading:21362310-Humans,
pubmed-meshheading:21362310-Interleukin-6,
pubmed-meshheading:21362310-Male,
pubmed-meshheading:21362310-Middle Aged,
pubmed-meshheading:21362310-Multivariate Analysis,
pubmed-meshheading:21362310-Tumor Necrosis Factor-alpha
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pubmed:year |
2011
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pubmed:articleTitle |
Polymorphism on chromosome 9p21.3 contributes to early-onset and severity of coronary artery disease in non-diabetic and type 2 diabetic patients.
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pubmed:affiliation |
Department of Cardiology, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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