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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2011-3-22
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pubmed:abstractText |
Preeclamptic women have increased plasma levels of free fetal hemoglobin (HbF), increased gene expression of placental HbF and accumulation of free HbF in the placental vascular lumen. Free hemoglobin (Hb) is pro-inflammatory, and causes oxidative stress and tissue damage.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1532-3102
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pubmed:author |
pubmed-author:AkerströmBB,
pubmed-author:CederlundMM,
pubmed-author:CentlowMM,
pubmed-author:HanssonS RSR,
pubmed-author:LarssonII,
pubmed-author:MörgelinMM,
pubmed-author:MayKK,
pubmed-author:OlssonM GMG,
pubmed-author:RosenlöfLL,
pubmed-author:RutardottirSS,
pubmed-author:SchneiderHH,
pubmed-author:SiegmundWW
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pubmed:copyrightInfo |
Copyright © 2011 Elsevier Ltd. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
32
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
323-32
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pubmed:meshHeading |
pubmed-meshheading:21356557-Alpha-Globulins,
pubmed-meshheading:21356557-Female,
pubmed-meshheading:21356557-Fetal Hemoglobin,
pubmed-meshheading:21356557-Gene Expression Profiling,
pubmed-meshheading:21356557-Hemoglobins,
pubmed-meshheading:21356557-Humans,
pubmed-meshheading:21356557-Oxidative Stress,
pubmed-meshheading:21356557-Perfusion,
pubmed-meshheading:21356557-Placenta,
pubmed-meshheading:21356557-Pre-Eclampsia,
pubmed-meshheading:21356557-Pregnancy,
pubmed-meshheading:21356557-Up-Regulation
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pubmed:year |
2011
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pubmed:articleTitle |
Perfusion of human placenta with hemoglobin introduces preeclampsia-like injuries that are prevented by ?1-microglobulin.
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pubmed:affiliation |
Division of Obstetrics and Gynecology, Department of Clinical Sciences, Lund University Hospital, Lund University, Lund, Sweden.
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
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