Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1992-6-1
pubmed:abstractText
Uptake of glucose, free fatty acids (FFA) and lactic acid was studied in soleus muscle of heparinized cats under pentobarbital anesthesia. Cats were separated in 3 groups: caged, "free" and exercised. Blood samples were taken from an artery and the venous effluent of the muscle, a) at rest, b) after contraction, c) after Intralipid infusion, d) after a post-infusion contraction. Glucose was released in some muscles in a) and b), but uptake predominated in c) and d). There was a direct relationship between glucose uptake and lactic acid production only in muscles of exercised cats in a). Venous FFA levels correlated with lactic acid release in b) and d). Results indicated that in the studied conditions soleus muscle of the cat, which is formed by slow oxidative fibres, utilized FFA as the main fuel; glycogen was used during contraction producing a non significant increase in lactic acid. The inhibition by FFA of pyruvate entrance to the TCA cycle, was suggested by the direct correlation between venous FFA levels and lactic acid release.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0001-5504
pubmed:author
pubmed:issnType
Print
pubmed:volume
41
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
33-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Effect of lipid infusion on substrate uptake in soleus muscle of the cat.
pubmed:affiliation
Departamento de Ciencias Fisiológicas, Facultad de Medicina, Universidad Central de Venezuela, Caracas.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't