Source:http://linkedlifedata.com/resource/pubmed/id/21353957
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
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| pubmed:dateCreated |
2011-2-28
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| pubmed:abstractText |
The CANWARD study (Canadian Ward Surveillance Study) assessed the antimicrobial susceptibility of a variety of available agents against 15 644 pathogens isolated from patients in Canadian hospitals between 2007 and 2009. The most active (based on MIC data) agents against methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci were daptomycin, linezolid, tigecycline, and vancomycin (MRSA only) with MIC(90)'s (?g/mL) of 0.25 and 2, 2 and 2, 0.5 and 0.12, and 1, respectively. The most active agents against extended-spectrum ?-lactamase-producing Escherichia coli were colistin (polymyxin E), doripenem, ertapenem, meropenem, and tigecycline with MIC(90)'s (?g/mL) of 1, ? 0.12, 0.25, ? 0.12, and 1, respectively. The most active agents against Pseudomonas aeruginosa were amikacin, cefepime, ceftazidime, colistin, doripenem, meropenem, and piperacillin-tazobactam with MIC(90)'s (?g/mL) of 32, 16, 32, 2, 4, 8, and 64, respectively. Overall, the most active agents versus Gram-positive cocci from Canadian hospitals were vancomycin, linezolid, daptomycin, and tigecycline and versus Gram-negative bacilli were amikacin, cefepime, doripenem, ertapenem (excluding Pseudomonas aeruginosa), meropenem, piperacillin-tazobactam, and tigecycline (excluding Pseudomonas aeruginosa).
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:chemical | |
| pubmed:status |
MEDLINE
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| pubmed:month |
Mar
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| pubmed:issn |
1879-0070
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| pubmed:author |
pubmed-author:AdamHeather JHJ,
pubmed-author:BlondeauJosephJ,
pubmed-author:Canadian Antimicrobial Resistance Alliance (CARA),
pubmed-author:DecorbyMelanieM,
pubmed-author:HobanDaryl JDJ,
pubmed-author:KarlowskyJames AJA,
pubmed-author:LowDonald EDE,
pubmed-author:VashishtRaviR,
pubmed-author:WeshnoweskiBarbaraB,
pubmed-author:WierzbowskiAleksandraA,
pubmed-author:ZhanelGeorge GGG
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| pubmed:copyrightInfo |
Copyright © 2011 Elsevier Inc. All rights reserved.
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| pubmed:issnType |
Electronic
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| pubmed:volume |
69
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| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
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| pubmed:pagination |
291-306
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| pubmed:meshHeading |
pubmed-meshheading:21353957-Adolescent,
pubmed-meshheading:21353957-Adult,
pubmed-meshheading:21353957-Aged,
pubmed-meshheading:21353957-Aged, 80 and over,
pubmed-meshheading:21353957-Anti-Bacterial Agents,
pubmed-meshheading:21353957-Bacterial Infections,
pubmed-meshheading:21353957-Canada,
pubmed-meshheading:21353957-Child,
pubmed-meshheading:21353957-Child, Preschool,
pubmed-meshheading:21353957-Drug Resistance, Bacterial,
pubmed-meshheading:21353957-Gram-Negative Bacteria,
pubmed-meshheading:21353957-Gram-Positive Cocci,
pubmed-meshheading:21353957-Hospitals,
pubmed-meshheading:21353957-Humans,
pubmed-meshheading:21353957-Infant,
pubmed-meshheading:21353957-Infant, Newborn,
pubmed-meshheading:21353957-Methicillin-Resistant Staphylococcus aureus,
pubmed-meshheading:21353957-Microbial Sensitivity Tests,
pubmed-meshheading:21353957-Middle Aged,
pubmed-meshheading:21353957-Vancomycin Resistance,
pubmed-meshheading:21353957-beta-Lactamases
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| pubmed:year |
2011
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| pubmed:articleTitle |
Antimicrobial susceptibility of 15,644 pathogens from Canadian hospitals: results of the CANWARD 2007-2009 study.
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| pubmed:affiliation |
Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Manitoba, Canada R3E 0J9. ggzhanel@pcs.mb.ca
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| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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