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pubmed-article:21353471pubmed:abstractTextAlthough the combination of doxorubicin (Dox) and trastuzumab (Trz) reduces breast cancer progression and recurrence, it is limited by significant cardiotoxic side effects. Little is known about the utility of antioxidants in the prevention of this drug-induced cardiomyopathy. The aim of the study was to determine whether the antioxidant probucol (Prob) would be useful in attenuating Dox and Trz-mediated cardiotoxicity.lld:pubmed
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pubmed-article:21353471pubmed:copyrightInfoCopyright © 2011 American Society of Echocardiography. Published by Mosby, Inc. All rights reserved.lld:pubmed
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pubmed-article:21353471pubmed:dateRevised2011-11-17lld:pubmed
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pubmed-article:21353471pubmed:articleTitleThe cardioprotective role of probucol against anthracycline and trastuzumab-mediated cardiotoxicity.lld:pubmed
pubmed-article:21353471pubmed:affiliationInstitute of Cardiovascular Sciences, St. Boniface Research Centre, University of Manitoba, 409 Tache Avenue, Winnipeg, Manitoba, Canada.lld:pubmed
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