Linked Life Data

21351246

Source:http://linkedlifedata.com/resource/pubmed/id/21351246

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2011-6-10
pubmed:abstractText
Because vertebrate jaw evolution involved modification of the anteriormost pharyngeal arch, it is important to understand the skeletal patterning of the lamprey pharyngeal arch. In this study, we visualized mucocartilage, which constitutes most of the skeletal elements in the anterior pharyngeal arches of the lamprey, and traced the development of these skeletal elements. We found that the basic framework of the mucocartilage skeletal elements is established in stage-30 larvae (about 1-month-old at 16 °C) and that the expression pattern of the SoxE homolog, LjSoxE3, prefigures the development of the skeletal elements in the craniofacial region. This enabled us to trace the developmental pattern of the anterior pharyngeal arch skeletal elements. We obtained evidence that endothelin signaling is involved in development of the ventral element of the first pharyngeal arch. These results suggest that endothelin signaling was already involved in the specification for the ventral skeleton and that the gnathostome jaw innovation must have been achieved by modifying downstream regulatory systems.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1552-5015
pubmed:author
pubmed:copyrightInfo
Copyright © 2011 Wiley-Liss, Inc.
pubmed:issnType
Electronic
pubmed:day
15
pubmed:volume
316
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
339-46
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
Development of lamprey mucocartilage and its dorsal-ventral patterning by endothelin signaling, with insight into vertebrate jaw evolution.
pubmed:affiliation
Graduate School of Life and Environmental Sciences, University of Tsukuba, Tsukuba, Japan.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't