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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
2011-5-31
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pubmed:abstractText |
The ability of PET to aid in the diagnosis and management of recurrent and/or disseminated metastatic prostate cancer may be enhanced by the development of novel prognostic imaging probes. Accumulating experimental evidence indicates that overexpression of integrin ?(2)?(1) may correlate with progression in human prostate cancer. In this study, (64)Cu-labeled integrin ?(2)?(1)-targeted PET probes were designed and evaluated for the imaging of prostate cancer.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1619-7089
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
38
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1313-22
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pubmed:meshHeading |
pubmed-meshheading:21350963-Animals,
pubmed-meshheading:21350963-Cell Line, Tumor,
pubmed-meshheading:21350963-Cell Transformation, Neoplastic,
pubmed-meshheading:21350963-Copper Radioisotopes,
pubmed-meshheading:21350963-Drug Design,
pubmed-meshheading:21350963-Drug Stability,
pubmed-meshheading:21350963-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:21350963-Humans,
pubmed-meshheading:21350963-Integrin alpha2beta1,
pubmed-meshheading:21350963-Male,
pubmed-meshheading:21350963-Mice,
pubmed-meshheading:21350963-Molecular Probes,
pubmed-meshheading:21350963-Oligopeptides,
pubmed-meshheading:21350963-Positron-Emission Tomography,
pubmed-meshheading:21350963-Prostatic Neoplasms,
pubmed-meshheading:21350963-Protein Transport,
pubmed-meshheading:21350963-Radiochemistry,
pubmed-meshheading:21350963-Reproducibility of Results
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pubmed:year |
2011
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pubmed:articleTitle |
Design, synthesis and validation of integrin ?2?1-targeted probe for microPET imaging of prostate cancer.
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pubmed:affiliation |
Department of Radiology, University of Southern California, 1510 San Pablo Street, Los Angeles, CA 90033, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
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